KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOM3Z
All Species:
4.24
Human Site:
Y314
Identified Species:
8.48
UniProt:
O77932
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O77932
NP_005501.2
396
44929
Y314
P
T
M
K
M
F
E
Y
V
R
N
D
R
D
G
Chimpanzee
Pan troglodytes
XP_001161885
396
44867
Y314
P
T
M
K
M
F
E
Y
V
R
N
D
G
D
G
Rhesus Macaque
Macaca mulatta
XP_001106541
251
28178
V170
T
M
K
M
F
D
Y
V
R
N
D
R
D
G
W
Dog
Lupus familis
XP_538842
347
39553
R266
M
E
M
F
E
Y
V
R
N
D
R
D
G
W
N
Cat
Felis silvestris
Mouse
Mus musculus
O70348
397
45262
N314
P
T
M
E
M
F
E
N
V
R
N
D
R
E
G
Rat
Rattus norvegicus
Q6MG77
397
45281
N314
P
T
M
E
M
F
E
N
V
R
N
D
Q
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512198
126
14180
R45
M
D
M
F
Q
L
V
R
D
D
R
E
A
W
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5HZT0
401
46175
I318
F
R
S
P
E
G
R
I
V
S
L
E
T
F
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10660
393
45840
Q309
I
I
V
G
L
R
T
Q
E
G
H
V
K
S
L
Sea Urchin
Strong. purpuratus
XP_783738
649
73632
M324
R
S
F
Q
T
M
Q
M
A
S
S
S
Q
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY73
544
60363
G453
V
V
G
F
R
D
D
G
G
R
L
V
R
T
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9HE87
383
44364
M296
R
T
M
E
I
P
L
M
V
K
K
N
G
R
P
Conservation
Percent
Protein Identity:
100
99.2
60.6
77.5
N.A.
90.1
90.4
N.A.
23.4
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
25.5
28.8
Protein Similarity:
100
99.4
62.3
81.3
N.A.
93.9
94.2
N.A.
29
N.A.
65.5
N.A.
N.A.
N.A.
N.A.
45.9
41.6
P-Site Identity:
100
93.3
0
13.3
N.A.
80
73.3
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
93.3
6.6
20
N.A.
93.3
93.3
N.A.
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
29.2
Protein Similarity:
N.A.
N.A.
N.A.
36.7
N.A.
43.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
17
9
0
9
17
9
42
9
17
0
% D
% Glu:
0
9
0
25
17
0
34
0
9
0
0
17
0
17
9
% E
% Phe:
9
0
9
25
9
34
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
9
9
0
9
0
9
9
9
0
0
25
17
34
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
9
0
0
9
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
17
0
0
0
0
0
9
9
0
9
0
9
% K
% Leu:
0
0
0
0
9
9
9
0
0
0
17
0
0
0
9
% L
% Met:
17
9
59
9
34
9
0
17
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
17
9
9
34
9
0
0
17
% N
% Pro:
34
0
0
9
0
9
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
9
9
0
9
9
0
0
0
0
17
0
0
% Q
% Arg:
17
9
0
0
9
9
9
17
9
42
17
9
25
9
0
% R
% Ser:
0
9
9
0
0
0
0
0
0
17
9
9
0
9
0
% S
% Thr:
9
42
0
0
9
0
9
0
0
0
0
0
9
9
0
% T
% Val:
9
9
9
0
0
0
17
9
50
0
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
9
% W
% Tyr:
0
0
0
0
0
9
9
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _