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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOM3Z All Species: 15.45
Human Site: Y36 Identified Species: 30.91
UniProt: O77932 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O77932 NP_005501.2 396 44929 Y36 L P T D P A L Y S G P F P F Y
Chimpanzee Pan troglodytes XP_001161885 396 44867 Y36 L P T D P A L Y S G P F P F Y
Rhesus Macaque Macaca mulatta XP_001106541 251 28178
Dog Lupus familis XP_538842 347 39553 H20 R G P E Q R C H P P G L A S C
Cat Felis silvestris
Mouse Mus musculus O70348 397 45262 Y36 L R T Q P S L Y S G P F P F Y
Rat Rattus norvegicus Q6MG77 397 45281 Y36 L R T Q P S L Y S G P F P F Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512198 126 14180
Chicken Gallus gallus
Frog Xenopus laevis Q5HZT0 401 46175 Y47 L K T L H S L Y Q G S F P F Y
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10660 393 45840 N47 E V Q I P F D N M I Y E T R N
Sea Urchin Strong. purpuratus XP_783738 649 73632 F47 P I K P I S R F N Q K F P F F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RY73 544 60363 I135 P A I S T Y S I P V L P A G W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9HE87 383 44364 G40 A D H K F L L G A Q S L K W Y
Conservation
Percent
Protein Identity: 100 99.2 60.6 77.5 N.A. 90.1 90.4 N.A. 23.4 N.A. 52.6 N.A. N.A. N.A. N.A. 25.5 28.8
Protein Similarity: 100 99.4 62.3 81.3 N.A. 93.9 94.2 N.A. 29 N.A. 65.5 N.A. N.A. N.A. N.A. 45.9 41.6
P-Site Identity: 100 100 0 0 N.A. 80 80 N.A. 0 N.A. 60 N.A. N.A. N.A. N.A. 6.6 20
P-Site Similarity: 100 100 0 13.3 N.A. 86.6 86.6 N.A. 0 N.A. 66.6 N.A. N.A. N.A. N.A. 6.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. 22 N.A. 29.2
Protein Similarity: N.A. N.A. N.A. 36.7 N.A. 43.4
P-Site Identity: N.A. N.A. N.A. 0 N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 17 0 0 9 0 0 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 9 % C
% Asp: 0 9 0 17 0 0 9 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 9 9 0 9 0 0 0 50 0 50 9 % F
% Gly: 0 9 0 0 0 0 0 9 0 42 9 0 0 9 0 % G
% His: 0 0 9 0 9 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 9 9 9 9 0 0 9 0 9 0 0 0 0 0 % I
% Lys: 0 9 9 9 0 0 0 0 0 0 9 0 9 0 0 % K
% Leu: 42 0 0 9 0 9 50 0 0 0 9 17 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 9 % N
% Pro: 17 17 9 9 42 0 0 0 17 9 34 9 50 0 0 % P
% Gln: 0 0 9 17 9 0 0 0 9 17 0 0 0 0 0 % Q
% Arg: 9 17 0 0 0 9 9 0 0 0 0 0 0 9 0 % R
% Ser: 0 0 0 9 0 34 9 0 34 0 17 0 0 9 0 % S
% Thr: 0 0 42 0 9 0 0 0 0 0 0 0 9 0 0 % T
% Val: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % W
% Tyr: 0 0 0 0 0 9 0 42 0 0 9 0 0 0 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _