KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECQL5
All Species:
23.94
Human Site:
S491
Identified Species:
52.67
UniProt:
O94762
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94762
NP_001003715.1
991
108858
S491
Y
D
E
G
S
G
G
S
G
D
E
G
R
D
E
Chimpanzee
Pan troglodytes
XP_001144082
991
108864
S491
Y
D
E
G
S
G
G
S
G
Y
E
G
R
D
E
Rhesus Macaque
Macaca mulatta
XP_001098095
991
108681
S491
Y
D
E
G
S
G
G
S
G
D
E
G
R
D
E
Dog
Lupus familis
XP_540436
989
108541
S488
Y
D
E
G
S
G
G
S
G
D
E
G
R
D
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_569721
982
108227
S492
Y
D
E
G
S
G
G
S
G
D
E
G
R
D
E
Rat
Rattus norvegicus
NP_001099323
973
107203
S492
Y
D
E
G
S
G
G
S
G
D
E
G
R
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519897
509
55570
C44
G
E
K
D
V
F
V
C
M
P
T
G
A
G
K
Chicken
Gallus gallus
XP_001233565
1018
112529
N467
Y
D
E
E
S
S
G
N
G
D
E
A
N
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694922
936
104014
F471
G
G
R
K
G
Y
G
F
E
R
H
D
E
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729983
1058
121182
S485
Q
E
Y
A
G
G
E
S
G
S
D
D
D
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795300
1122
123964
D550
G
K
K
R
K
P
G
D
W
S
D
D
D
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
95.9
83.4
N.A.
78.8
76.8
N.A.
39.4
57.5
N.A.
47.9
N.A.
34
N.A.
N.A.
35.2
Protein Similarity:
100
99.2
97.2
88.5
N.A.
85.8
84.4
N.A.
44.4
71.2
N.A.
62.7
N.A.
48.7
N.A.
N.A.
49.9
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
6.6
60
N.A.
6.6
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
26.6
73.3
N.A.
13.3
N.A.
33.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
64
0
10
0
0
0
10
0
55
19
28
19
64
0
% D
% Glu:
0
19
64
10
0
0
10
0
10
0
64
0
10
19
64
% E
% Phe:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
10
% F
% Gly:
28
10
0
55
19
64
82
0
73
0
0
64
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
19
10
10
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
0
0
0
0
10
0
0
55
0
0
% R
% Ser:
0
0
0
0
64
10
0
64
0
19
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
64
0
10
0
0
10
0
0
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _