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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECQL5
All Species:
17.27
Human Site:
S649
Identified Species:
38
UniProt:
O94762
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94762
NP_001003715.1
991
108858
S649
P
P
A
S
H
V
Y
S
L
K
P
K
R
V
G
Chimpanzee
Pan troglodytes
XP_001144082
991
108864
S649
P
P
A
S
H
V
Y
S
L
K
P
K
R
V
G
Rhesus Macaque
Macaca mulatta
XP_001098095
991
108681
S649
P
P
A
S
H
V
Y
S
L
K
P
K
R
V
G
Dog
Lupus familis
XP_540436
989
108541
S646
R
P
A
S
Q
V
Y
S
L
K
P
K
R
V
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_569721
982
108227
S650
P
P
T
S
H
V
Y
S
L
K
P
K
R
V
G
Rat
Rattus norvegicus
NP_001099323
973
107203
A632
T
K
S
C
G
A
I
A
E
L
L
E
P
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519897
509
55570
V182
R
L
P
H
T
P
C
V
A
L
T
A
T
A
P
Chicken
Gallus gallus
XP_001233565
1018
112529
V626
D
F
L
P
A
S
Q
V
Y
S
F
K
P
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694922
936
104014
P609
V
S
V
T
E
E
K
P
C
E
S
A
E
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729983
1058
121182
K663
A
Y
F
E
R
K
L
K
E
L
E
E
Q
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795300
1122
123964
L762
D
N
L
G
C
S
F
L
E
G
E
E
F
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
95.9
83.4
N.A.
78.8
76.8
N.A.
39.4
57.5
N.A.
47.9
N.A.
34
N.A.
N.A.
35.2
Protein Similarity:
100
99.2
97.2
88.5
N.A.
85.8
84.4
N.A.
44.4
71.2
N.A.
62.7
N.A.
48.7
N.A.
N.A.
49.9
P-Site Identity:
100
100
100
86.6
N.A.
93.3
0
N.A.
0
6.6
N.A.
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
20
N.A.
0
6.6
N.A.
13.3
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
37
0
10
10
0
10
10
0
0
19
0
10
0
% A
% Cys:
0
0
0
10
10
0
10
0
10
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% D
% Glu:
0
0
0
10
10
10
0
0
28
10
19
28
10
10
0
% E
% Phe:
0
10
10
0
0
0
10
0
0
0
10
0
10
0
0
% F
% Gly:
0
0
0
10
10
0
0
0
0
10
0
0
0
0
46
% G
% His:
0
0
0
10
37
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
10
10
10
0
46
0
55
0
10
10
% K
% Leu:
0
10
19
0
0
0
10
10
46
28
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
37
46
10
10
0
10
0
10
0
0
46
0
19
0
19
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
0
0
10
0
0
% Q
% Arg:
19
0
0
0
10
0
0
0
0
0
0
0
46
10
10
% R
% Ser:
0
10
10
46
0
19
0
46
0
10
10
0
0
10
0
% S
% Thr:
10
0
10
10
10
0
0
0
0
0
10
0
10
0
0
% T
% Val:
10
0
10
0
0
46
0
19
0
0
0
0
0
46
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
46
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _