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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RECQL5 All Species: 9.09
Human Site: S727 Identified Species: 20
UniProt: O94762 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94762 NP_001003715.1 991 108858 S727 S A H Y G G P S P E K K A K S
Chimpanzee Pan troglodytes XP_001144082 991 108864 S727 S A H Y G G P S P E K K A K S
Rhesus Macaque Macaca mulatta XP_001098095 991 108681 S727 S A H C G G P S P E K K A K S
Dog Lupus familis XP_540436 989 108541 P725 F H C G G S S P E K T G K S P
Cat Felis silvestris
Mouse Mus musculus NP_569721 982 108227 D726 G S S V N C G D P S P E K K T
Rat Rattus norvegicus NP_001099323 973 107203 P709 Q D G D R S K P C L G Y Q E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519897 509 55570 G256 R G A F S G C G I V Y C R T R
Chicken Gallus gallus XP_001233565 1018 112529 S753 K K E S Q D I S K F F S L S K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694922 936 104014 D683 E S G K T Q K D N N N T S S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_729983 1058 121182 N738 T P K D I A S N H V K E E S V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795300 1122 123964 E858 I K A V R T L E Q L G E M S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 95.9 83.4 N.A. 78.8 76.8 N.A. 39.4 57.5 N.A. 47.9 N.A. 34 N.A. N.A. 35.2
Protein Similarity: 100 99.2 97.2 88.5 N.A. 85.8 84.4 N.A. 44.4 71.2 N.A. 62.7 N.A. 48.7 N.A. N.A. 49.9
P-Site Identity: 100 100 93.3 6.6 N.A. 13.3 0 N.A. 6.6 6.6 N.A. 0 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 13.3 N.A. 33.3 6.6 N.A. 13.3 6.6 N.A. 13.3 N.A. 26.6 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 28 19 0 0 10 0 0 0 0 0 0 28 0 0 % A
% Cys: 0 0 10 10 0 10 10 0 10 0 0 10 0 0 0 % C
% Asp: 0 10 0 19 0 10 0 19 0 0 0 0 0 0 0 % D
% Glu: 10 0 10 0 0 0 0 10 10 28 0 28 10 10 10 % E
% Phe: 10 0 0 10 0 0 0 0 0 10 10 0 0 0 0 % F
% Gly: 10 10 19 10 37 37 10 10 0 0 19 10 0 0 10 % G
% His: 0 10 28 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 10 0 10 0 10 0 0 0 0 0 10 % I
% Lys: 10 19 10 10 0 0 19 0 10 10 37 28 19 37 10 % K
% Leu: 0 0 0 0 0 0 10 0 0 19 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 10 0 0 10 10 10 10 0 0 0 0 % N
% Pro: 0 10 0 0 0 0 28 19 37 0 10 0 0 0 10 % P
% Gln: 10 0 0 0 10 10 0 0 10 0 0 0 10 0 0 % Q
% Arg: 10 0 0 0 19 0 0 0 0 0 0 0 10 0 10 % R
% Ser: 28 19 10 10 10 19 19 37 0 10 0 10 10 46 28 % S
% Thr: 10 0 0 0 10 10 0 0 0 0 10 10 0 10 10 % T
% Val: 0 0 0 19 0 0 0 0 0 19 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 19 0 0 0 0 0 0 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _