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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ECM2 All Species: 11.21
Human Site: S75 Identified Species: 35.24
UniProt: O94769 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94769 NP_001384.1 699 79789 S75 P I V N F D Y S M E E K F E S
Chimpanzee Pan troglodytes XP_001148362 731 83077 S160 P I V N F D Y S M E E K F E S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533562 727 82147 S129 P V L N L D Y S T E E K S D S
Cat Felis silvestris
Mouse Mus musculus Q5FW85 670 76657 S70 P T A N S D Y S V E E N I E S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521514 591 67784 L70 D E E S I S K L K S L L P S P
Chicken Gallus gallus XP_414297 670 76174 N71 K K G Q C T A N G M I M F D K
Frog Xenopus laevis NP_001087658 364 40190
Zebra Danio Brachydanio rerio XP_686507 742 84406 D72 T P E S N G Q D R S V F M E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85 N.A. 72.6 N.A. 73.5 N.A. N.A. 57 57.6 21.3 46 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 86.7 N.A. 80.1 N.A. 83.2 N.A. N.A. 67.5 71.8 31.3 61.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 60 N.A. 60 N.A. N.A. 0 6.6 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 80 N.A. 66.6 N.A. N.A. 6.6 20 0 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 0 0 13 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 0 0 50 0 13 0 0 0 0 0 25 0 % D
% Glu: 0 13 25 0 0 0 0 0 0 50 50 0 0 50 0 % E
% Phe: 0 0 0 0 25 0 0 0 0 0 0 13 38 0 0 % F
% Gly: 0 0 13 0 0 13 0 0 13 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 25 0 0 13 0 0 0 0 0 13 0 13 0 0 % I
% Lys: 13 13 0 0 0 0 13 0 13 0 0 38 0 0 13 % K
% Leu: 0 0 13 0 13 0 0 13 0 0 13 13 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 25 13 0 13 13 0 0 % M
% Asn: 0 0 0 50 13 0 0 13 0 0 0 13 0 0 0 % N
% Pro: 50 13 0 0 0 0 0 0 0 0 0 0 13 0 13 % P
% Gln: 0 0 0 13 0 0 13 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % R
% Ser: 0 0 0 25 13 13 0 50 0 25 0 0 13 13 63 % S
% Thr: 13 13 0 0 0 13 0 0 13 0 0 0 0 0 0 % T
% Val: 0 13 25 0 0 0 0 0 13 0 13 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _