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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPM2 All Species: 24.85
Human Site: Y43 Identified Species: 68.33
UniProt: O94777 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94777 NP_003854.1 84 9312 Y43 S Q H V I H K Y F L P R A Y A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093450 84 9296 Y43 S E H V I H K Y F L P R A Y A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9Z324 84 9358 Y43 S Q H V I H K Y F L P R A Y A
Rat Rattus norvegicus Q9Z325 84 9326 Y43 S Q H V I H K Y F L P R A Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518742 132 15072 Y91 S D H V I H K Y F L P R E Y A
Chicken Gallus gallus XP_001234807 130 14139 Y89 S D H S I H Q Y F L P R E Y A
Frog Xenopus laevis NP_001165179 84 9423 F43 N D H V I H S F F L P R E Y A
Zebra Danio Brachydanio rerio NP_001116318 83 9227 Y43 S D H V I H S Y F L P R E Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002326543 80 9200 L44 H F V H Q Y F L P Q E Y A I L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.2 N.A. N.A. 88 88 N.A. 47.7 41.5 59.5 59.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 100 N.A. N.A. 95.2 95.2 N.A. 56 52.3 80.9 72.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 93.3 N.A. N.A. 100 100 N.A. 86.6 73.3 66.6 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 86.6 80 80 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 51.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 72.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 56 0 78 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 45 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 12 0 0 0 0 0 0 0 0 12 0 45 0 0 % E
% Phe: 0 12 0 0 0 0 12 12 89 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 12 0 89 12 0 89 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 89 0 0 0 0 0 0 0 0 12 0 % I
% Lys: 0 0 0 0 0 0 56 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 12 0 89 0 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 12 0 89 0 0 0 0 % P
% Gln: 0 34 0 0 12 0 12 0 0 12 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 89 0 0 0 % R
% Ser: 78 0 0 12 0 0 23 0 0 0 0 0 0 0 12 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 12 78 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 78 0 0 0 12 0 89 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _