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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP1
All Species:
16.06
Human Site:
S253
Identified Species:
32.12
UniProt:
O94782
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94782
NP_001017415.1
785
88207
S253
I
N
S
I
E
M
D
S
M
R
H
S
E
D
F
Chimpanzee
Pan troglodytes
XP_513450
785
88166
S253
I
N
S
M
E
M
D
S
M
R
H
S
E
D
F
Rhesus Macaque
Macaca mulatta
XP_001085195
784
88189
S252
I
N
S
M
E
M
D
S
V
R
H
S
E
D
C
Dog
Lupus familis
XP_865460
785
88368
N253
I
N
S
I
E
M
D
N
L
R
P
S
E
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJQ2
784
87438
S253
I
T
S
T
E
I
D
S
M
R
N
T
E
D
V
Rat
Rattus norvegicus
Q569C3
784
87311
S253
I
S
S
T
E
T
D
S
T
R
N
L
D
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026461
794
88314
E258
G
N
S
A
E
E
E
E
E
N
A
P
G
S
H
Frog
Xenopus laevis
Q52KZ6
370
42846
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001128140
646
73202
S159
S
G
S
R
S
W
S
S
K
D
L
L
A
L
A
Nematode Worm
Caenorhab. elegans
P34547
426
48259
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146737
368
41784
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAM0
365
41828
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.3
94.3
N.A.
88.5
88.6
N.A.
N.A.
73.1
20.5
N.A.
N.A.
N.A.
21.7
22.5
N.A.
Protein Similarity:
100
100
98.5
96.5
N.A.
93.2
92.6
N.A.
N.A.
82.4
32.8
N.A.
N.A.
N.A.
38.8
36.4
N.A.
P-Site Identity:
100
93.3
80
73.3
N.A.
60
46.6
N.A.
N.A.
20
0
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
66.6
N.A.
N.A.
26.6
0
N.A.
N.A.
N.A.
13.3
0
N.A.
Percent
Protein Identity:
N.A.
21.4
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
31.5
N.A.
30.4
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
9
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
50
0
0
9
0
0
9
50
0
% D
% Glu:
0
0
0
0
59
9
9
9
9
0
0
0
42
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% F
% Gly:
9
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
9
% H
% Ile:
50
0
0
17
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
9
0
9
17
0
9
9
% L
% Met:
0
0
0
17
0
34
0
0
25
0
0
0
0
0
0
% M
% Asn:
0
42
0
0
0
0
0
9
0
9
17
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
50
0
0
0
0
0
% R
% Ser:
9
9
67
0
9
0
9
50
0
0
0
34
0
9
0
% S
% Thr:
0
9
0
17
0
9
0
0
9
0
0
9
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _