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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP1
All Species:
26.36
Human Site:
S605
Identified Species:
52.73
UniProt:
O94782
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94782
NP_001017415.1
785
88207
S605
V
K
V
T
D
L
N
S
L
E
L
D
K
G
N
Chimpanzee
Pan troglodytes
XP_513450
785
88166
S605
V
K
V
T
D
L
N
S
L
E
L
D
K
G
N
Rhesus Macaque
Macaca mulatta
XP_001085195
784
88189
S604
V
K
V
T
D
L
N
S
L
E
L
D
K
G
N
Dog
Lupus familis
XP_865460
785
88368
S605
V
K
V
T
D
L
N
S
L
E
L
D
K
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJQ2
784
87438
S604
V
K
V
T
D
L
N
S
L
E
L
D
E
G
N
Rat
Rattus norvegicus
Q569C3
784
87311
S605
V
K
V
T
D
L
N
S
L
E
L
D
K
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026461
794
88314
L616
K
I
T
D
L
N
S
L
E
L
D
K
G
N
F
Frog
Xenopus laevis
Q52KZ6
370
42846
H214
E
Q
N
T
S
I
T
H
C
L
R
G
F
S
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001128140
646
73202
R490
E
C
N
N
D
Q
S
R
T
T
G
G
R
S
E
Nematode Worm
Caenorhab. elegans
P34547
426
48259
R270
S
K
Q
E
A
Q
K
R
M
R
I
K
K
P
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146737
368
41784
S212
E
Q
N
S
S
I
T
S
C
L
K
N
F
C
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAM0
365
41828
S209
E
Q
N
S
S
I
T
S
C
L
K
N
F
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.3
94.3
N.A.
88.5
88.6
N.A.
N.A.
73.1
20.5
N.A.
N.A.
N.A.
21.7
22.5
N.A.
Protein Similarity:
100
100
98.5
96.5
N.A.
93.2
92.6
N.A.
N.A.
82.4
32.8
N.A.
N.A.
N.A.
38.8
36.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
0
13.3
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
26.6
N.A.
N.A.
N.A.
20
26.6
N.A.
Percent
Protein Identity:
N.A.
21.4
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
31.5
N.A.
30.4
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
25
0
0
0
0
9
0
% C
% Asp:
0
0
0
9
59
0
0
0
0
0
9
50
0
0
0
% D
% Glu:
34
0
0
9
0
0
0
0
9
50
0
0
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
17
9
50
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
25
0
0
0
0
9
0
0
0
0
% I
% Lys:
9
59
0
0
0
0
9
0
0
0
17
17
50
0
0
% K
% Leu:
0
0
0
0
9
50
0
9
50
34
50
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
34
9
0
9
50
0
0
0
0
17
0
9
59
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% P
% Gln:
0
25
9
0
0
17
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
17
0
9
9
0
9
0
0
% R
% Ser:
9
0
0
17
25
0
17
67
0
0
0
0
0
25
17
% S
% Thr:
0
0
9
59
0
0
25
0
9
9
0
0
0
0
0
% T
% Val:
50
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _