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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1A2
All Species:
39.39
Human Site:
S331
Identified Species:
72.22
UniProt:
O94788
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94788
NP_003879.2
518
56724
S331
S
R
I
F
V
E
E
S
I
Y
E
E
F
V
R
Chimpanzee
Pan troglodytes
XP_001172122
497
54634
S310
S
R
I
F
V
E
E
S
I
Y
E
E
F
V
R
Rhesus Macaque
Macaca mulatta
XP_001090504
481
52697
S294
S
R
I
F
V
E
E
S
I
Y
E
E
F
V
R
Dog
Lupus familis
XP_535494
518
56685
S331
S
R
I
F
V
E
E
S
I
Y
E
E
F
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q62148
518
56607
S331
S
R
I
F
V
E
E
S
I
Y
E
E
F
V
K
Rat
Rattus norvegicus
Q63639
518
56621
S331
S
R
I
F
V
E
E
S
I
Y
E
E
F
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506070
601
66397
P414
S
R
I
F
V
E
E
P
I
Y
D
E
F
V
R
Chicken
Gallus gallus
O93344
518
56713
S331
S
R
I
Y
V
E
E
S
I
Y
E
E
F
V
R
Frog
Xenopus laevis
Q6GNL7
902
99964
S718
G
R
L
F
L
E
E
S
I
H
D
E
F
V
K
Zebra Danio
Brachydanio rerio
NP_571925
518
56497
P331
S
R
I
F
V
E
E
P
I
Y
D
E
F
V
R
Tiger Blowfish
Takifugu rubipres
NP_001028811
502
54691
S331
S
R
I
Y
V
E
E
S
I
H
D
E
F
V
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
K350
S
R
T
F
V
H
E
K
V
Y
D
E
F
V
E
Baker's Yeast
Sacchar. cerevisiae
P32872
511
56448
S342
S
R
I
T
V
H
E
S
I
Y
D
E
I
V
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
92
99.6
N.A.
97.3
97.4
N.A.
62.9
95.9
31.8
79.5
77.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.2
92.6
99.8
N.A.
98.4
98.4
N.A.
76
98.2
41.5
91.6
88.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
93.3
60
86.6
80
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
93.3
93.3
100
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
52.6
53
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.7
70.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% D
% Glu:
0
0
0
0
0
85
100
0
0
0
54
100
0
0
16
% E
% Phe:
0
0
0
77
0
0
0
0
0
0
0
0
93
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
16
0
0
0
16
0
0
0
0
0
% H
% Ile:
0
0
85
0
0
0
0
0
93
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
24
% K
% Leu:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
62
% R
% Ser:
93
0
0
0
0
0
0
77
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
93
0
0
0
8
0
0
0
0
100
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
0
0
0
0
85
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _