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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH1A2 All Species: 31.82
Human Site: S351 Identified Species: 58.33
UniProt: O94788 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94788 NP_003879.2 518 56724 S351 A K R R V V G S P F D P T T E
Chimpanzee Pan troglodytes XP_001172122 497 54634 S330 A K R R I V G S P F D P T T E
Rhesus Macaque Macaca mulatta XP_001090504 481 52697 S314 A K R R I V G S P F D P T T E
Dog Lupus familis XP_535494 518 56685 S351 A K R R I V G S P F D P T T E
Cat Felis silvestris
Mouse Mus musculus Q62148 518 56607 S351 A K R R I V G S P F D P T T E
Rat Rattus norvegicus Q63639 518 56621 S351 A K R R I V G S P F D P T T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506070 601 66397 N434 A K R Y T L G N P L T P G V E
Chicken Gallus gallus O93344 518 56713 S351 A K R R V V G S P F D P T T E
Frog Xenopus laevis Q6GNL7 902 99964 D738 V K K M K I G D P L D R S T D
Zebra Danio Brachydanio rerio NP_571925 518 56497 N351 A Q R R K V G N P F D P T T E
Tiger Blowfish Takifugu rubipres NP_001028811 502 54691 S351 A K R R I V G S P F D P T T E
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SU63 538 58570 D370 A L K R V V G D P F R K G I E
Baker's Yeast Sacchar. cerevisiae P32872 511 56448 N362 A K K Q V L G N P F E S D T R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 92 99.6 N.A. 97.3 97.4 N.A. 62.9 95.9 31.8 79.5 77.6 N.A. N.A. N.A. N.A.
Protein Similarity: 100 94.2 92.6 99.8 N.A. 98.4 98.4 N.A. 76 98.2 41.5 91.6 88.8 N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 93.3 N.A. 93.3 93.3 N.A. 46.6 100 33.3 80 93.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 60 100 60 93.3 100 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 52.6 53 N.A.
Protein Similarity: N.A. N.A. N.A. 68.7 70.2 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 16 0 0 77 0 8 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 85 % E
% Phe: 0 0 0 0 0 0 0 0 0 85 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 100 0 0 0 0 0 16 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 47 8 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 85 24 0 16 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 0 8 0 0 0 16 0 0 0 16 0 0 0 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 24 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 100 0 0 77 0 0 0 % P
% Gln: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 77 77 0 0 0 0 0 0 8 8 0 0 8 % R
% Ser: 0 0 0 0 0 0 0 62 0 0 0 8 8 0 0 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 8 0 70 85 0 % T
% Val: 8 0 0 0 31 77 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _