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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL6B
All Species:
23.64
Human Site:
S309
Identified Species:
40
UniProt:
O94805
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94805
NP_057272.1
426
46877
S309
P
E
G
L
F
D
P
S
N
V
K
G
L
S
G
Chimpanzee
Pan troglodytes
XP_001140943
374
41374
S263
P
S
N
V
K
G
L
S
G
N
T
M
L
G
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850533
409
44735
R298
N
T
D
Y
G
A
E
R
L
R
I
P
E
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99MR0
426
46873
S309
P
E
G
L
F
D
P
S
N
V
K
G
L
S
G
Rat
Rattus norvegicus
NP_001034122
429
47402
S312
P
E
G
L
F
D
P
S
N
V
K
G
L
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521333
303
33827
L191
D
P
S
N
V
K
G
L
S
G
N
T
M
L
G
Chicken
Gallus gallus
XP_422784
720
79965
S603
P
E
G
L
F
D
P
S
N
V
K
G
L
S
G
Frog
Xenopus laevis
NP_001080451
429
47605
S312
P
E
G
L
F
D
P
S
N
V
K
G
L
S
G
Zebra Danio
Brachydanio rerio
NP_775347
429
47223
S312
P
E
G
L
F
D
P
S
N
A
K
G
L
S
G
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
P266
C
P
E
T
L
F
Q
P
S
F
I
G
M
E
S
Fruit Fly
Dros. melanogaster
NP_611209
425
47301
K308
D
F
G
S
E
R
F
K
I
A
E
S
L
F
D
Honey Bee
Apis mellifera
XP_625202
440
49061
Q323
L
F
D
P
S
M
V
Q
M
R
G
G
M
V
G
Nematode Worm
Caenorhab. elegans
P10986
376
41759
P265
C
P
E
A
L
F
Q
P
S
F
L
G
M
E
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M92
441
48918
M324
I
V
Q
T
I
P
G
M
E
K
Y
A
E
M
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
N.A.
93.9
N.A.
99.7
84.1
N.A.
64
52.2
83.6
83.6
36.3
57.2
60.6
36.8
N.A.
Protein Similarity:
100
87.7
N.A.
95
N.A.
100
92.5
N.A.
68.3
56.2
91.8
92.3
54.2
75.1
77.2
54.2
N.A.
P-Site Identity:
100
20
N.A.
0
N.A.
100
100
N.A.
6.6
100
100
93.3
6.6
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
26.6
N.A.
0
N.A.
100
100
N.A.
20
100
100
93.3
20
20
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
0
15
0
8
0
0
0
% A
% Cys:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
15
0
0
43
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
43
15
0
8
0
8
0
8
0
8
0
15
15
0
% E
% Phe:
0
15
0
0
43
15
8
0
0
15
0
0
0
8
0
% F
% Gly:
0
0
50
0
8
8
15
0
8
8
8
65
0
15
58
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
8
0
15
0
0
0
8
% I
% Lys:
0
0
0
0
8
8
0
8
0
8
43
0
0
0
0
% K
% Leu:
8
0
0
43
15
0
8
8
8
0
8
0
58
8
8
% L
% Met:
0
0
0
0
0
8
0
8
8
0
0
8
29
8
0
% M
% Asn:
8
0
8
8
0
0
0
0
43
8
8
0
0
0
0
% N
% Pro:
50
22
0
8
0
8
43
15
0
0
0
8
0
0
0
% P
% Gln:
0
0
8
0
0
0
15
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
8
0
15
0
0
0
0
0
% R
% Ser:
0
8
8
8
8
0
0
50
22
0
0
8
0
43
15
% S
% Thr:
0
8
0
15
0
0
0
0
0
0
8
8
0
0
0
% T
% Val:
0
8
0
8
8
0
8
0
0
36
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _