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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTL6B All Species: 30
Human Site: S372 Identified Species: 50.77
UniProt: O94805 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94805 NP_057272.1 426 46877 S372 L S Q K T P P S M R L K L I A
Chimpanzee Pan troglodytes XP_001140943 374 41374 I326 P S M R L K L I A S N S T M E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850533 409 44735 L361 L Q G F T D R L N R E L S Q K
Cat Felis silvestris
Mouse Mus musculus Q99MR0 426 46873 S372 L S Q K T P P S M R L K L I A
Rat Rattus norvegicus NP_001034122 429 47402 S375 L S Q K T P P S M R L K L I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521333 303 33827 L254 P P S M R L K L I A N N T T V
Chicken Gallus gallus XP_422784 720 79965 S666 L S Q K T P P S M R L K L I A
Frog Xenopus laevis NP_001080451 429 47605 S375 L S Q K T P P S M R L K L I A
Zebra Danio Brachydanio rerio NP_775347 429 47223 S375 L S Q K T P P S M R L K L I A
Tiger Blowfish Takifugu rubipres P53480 377 41956 I329 L A P S T M K I K I I A P P E
Fruit Fly Dros. melanogaster NP_611209 425 47301 N371 L Q L R A P S N T R L K M I S
Honey Bee Apis mellifera XP_625202 440 49061 S386 L S M R I P S S M R L K L I S
Nematode Worm Caenorhab. elegans P10986 376 41759 I328 L A P S T M K I K I I A P P E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M92 441 48918 S387 L I E E S P H S A R V K V L A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.7 N.A. 93.9 N.A. 99.7 84.1 N.A. 64 52.2 83.6 83.6 36.3 57.2 60.6 36.8 N.A.
Protein Similarity: 100 87.7 N.A. 95 N.A. 100 92.5 N.A. 68.3 56.2 91.8 92.3 54.2 75.1 77.2 54.2 N.A.
P-Site Identity: 100 6.6 N.A. 20 N.A. 100 100 N.A. 0 100 100 100 13.3 40 66.6 13.3 N.A.
P-Site Similarity: 100 20 N.A. 20 N.A. 100 100 N.A. 6.6 100 100 100 26.6 66.6 80 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 42.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 63.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 80 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 8 0 0 0 15 8 0 15 0 0 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 8 0 0 0 0 0 0 8 0 0 0 22 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 8 0 0 22 8 15 15 0 0 58 0 % I
% Lys: 0 0 0 43 0 8 22 0 15 0 0 65 0 0 8 % K
% Leu: 86 0 8 0 8 8 8 15 0 0 58 8 50 8 0 % L
% Met: 0 0 15 8 0 15 0 0 50 0 0 0 8 8 0 % M
% Asn: 0 0 0 0 0 0 0 8 8 0 15 8 0 0 0 % N
% Pro: 15 8 15 0 0 65 43 0 0 0 0 0 15 15 0 % P
% Gln: 0 15 43 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 22 8 0 8 0 0 72 0 0 0 0 0 % R
% Ser: 0 58 8 15 8 0 15 58 0 8 0 8 8 0 15 % S
% Thr: 0 0 0 0 65 0 0 0 8 0 0 0 15 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _