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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKD3
All Species:
30
Human Site:
Y279
Identified Species:
82.5
UniProt:
O94806
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94806
NP_005804.1
890
100471
Y279
H
T
F
A
V
H
S
Y
T
R
P
T
I
C
Q
Chimpanzee
Pan troglodytes
XP_515412
914
103213
Y279
H
T
F
A
V
H
S
Y
T
R
P
T
I
C
Q
Rhesus Macaque
Macaca mulatta
XP_001108366
890
100428
Y279
H
T
F
A
V
H
S
Y
T
R
P
T
I
C
Q
Dog
Lupus familis
XP_540151
890
100382
Y279
H
T
F
A
V
H
S
Y
T
R
P
T
I
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1Y2
889
100060
Y279
H
T
F
A
V
H
S
Y
G
R
P
T
I
C
Q
Rat
Rattus norvegicus
Q9WTQ1
918
102025
Y284
H
T
F
V
I
H
S
Y
T
R
P
T
V
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509033
744
83197
P201
K
R
C
A
F
K
I
P
N
N
C
S
G
V
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685483
891
100383
Y277
H
T
F
V
I
H
T
Y
T
R
P
T
I
C
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45818
1070
120565
Y481
H
T
F
Q
V
H
S
Y
K
L
P
T
V
C
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
99.5
97.1
N.A.
95.7
68.4
N.A.
76.4
N.A.
N.A.
82
N.A.
N.A.
N.A.
45.1
N.A.
Protein Similarity:
100
97.3
99.6
98.7
N.A.
97.8
79
N.A.
79.7
N.A.
N.A.
89.4
N.A.
N.A.
N.A.
57.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
80
N.A.
6.6
N.A.
N.A.
80
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
12
0
0
89
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
89
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% G
% His:
89
0
0
0
0
89
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
23
0
12
0
0
0
0
0
67
0
0
% I
% Lys:
12
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
89
0
0
0
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
89
% Q
% Arg:
0
12
0
0
0
0
0
0
0
78
0
0
0
0
12
% R
% Ser:
0
0
0
0
0
0
78
0
0
0
0
12
0
0
0
% S
% Thr:
0
89
0
0
0
0
12
0
67
0
0
89
0
0
0
% T
% Val:
0
0
0
23
67
0
0
0
0
0
0
0
23
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
89
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _