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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPPP All Species: 26.97
Human Site: Y205 Identified Species: 59.33
UniProt: O94811 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94811 NP_008961.1 219 23694 Y205 E S G Y V S G Y K H A G T Y D
Chimpanzee Pan troglodytes XP_517605 219 23707 Y205 E S G Y V S G Y K H A G T Y D
Rhesus Macaque Macaca mulatta XP_001095130 219 23689 Y205 E S G Y V S G Y K H A G T Y D
Dog Lupus familis XP_545196 339 36934 Y325 E S G Y V P G Y K H A G T Y D
Cat Felis silvestris
Mouse Mus musculus Q7TQD2 218 23556 Y204 E S G Y V P G Y K H A G T Y D
Rat Rattus norvegicus Q5PPN5 176 18961 A163 D D S G Y V S A Y K N A G T Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505656 252 27673 Y238 D S G Y V P G Y K H A G T Y D
Chicken Gallus gallus XP_418894 235 25625 Y221 A S G Y V S G Y K H A G T Y D
Frog Xenopus laevis Q2VPM9 176 19075 S163 E N T G Y V G S Y K L A G T Y
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VV43 192 20578 V179 V V D G S G Y V S G Y Q H K D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91127 180 19387 A167 E N T G Y V G A Y K N K D S Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 99 61 N.A. 92.2 53.8 N.A. 73 76.1 50.6 N.A. N.A. 36.5 N.A. 33.7 N.A.
Protein Similarity: 100 99 99.5 63.7 N.A. 96.3 66.6 N.A. 79.3 85.5 66.2 N.A. N.A. 56.1 N.A. 48.8 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 0 N.A. 86.6 93.3 13.3 N.A. N.A. 6.6 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 6.6 N.A. 93.3 93.3 20 N.A. N.A. 6.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 19 0 0 64 19 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 10 10 0 0 0 0 0 0 0 0 0 10 0 73 % D
% Glu: 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 64 37 0 10 82 0 0 10 0 64 19 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 64 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 64 28 0 10 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 19 0 0 0 0 0 0 0 0 19 0 0 0 0 % N
% Pro: 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 64 10 0 10 37 10 10 10 0 0 0 0 10 0 % S
% Thr: 0 0 19 0 0 0 0 0 0 0 0 0 64 19 0 % T
% Val: 10 10 0 0 64 28 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 64 28 0 10 64 28 0 10 0 0 64 28 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _