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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLIT2 All Species: 31.82
Human Site: S1175 Identified Species: 63.64
UniProt: O94813 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94813 NP_004778.1 1529 169870 S1175 E S Y L Q I P S A K V R P Q T
Chimpanzee Pan troglodytes XP_001163449 1529 169849 S1175 E S Y L Q I P S A K V W P Q T
Rhesus Macaque Macaca mulatta XP_001094231 1706 186396 Q1353 V D R D T Y L Q F T D L Q N W
Dog Lupus familis XP_854843 1530 169605 S1175 E S Y L Q I P S A K V R P Q T
Cat Felis silvestris
Mouse Mus musculus Q9R1B9 1521 168752 S1167 E S Y L Q I P S A K V R P Q T
Rat Rattus norvegicus O88280 1523 167750 S1173 D S Y V E L A S A K V R P Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513256 1471 163510 S1117 E S Y L Q I L S T K L R P Q T
Chicken Gallus gallus XP_001232041 1528 169378 S1174 E S Y L Q I P S A K I H S Q T
Frog Xenopus laevis NP_001081137 1530 170084 S1176 D S F I P I P S T K I R A Q A
Zebra Danio Brachydanio rerio NP_571810 1512 166652 S1158 E S F L Q I P S N L I T E Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24014 1504 168581 Y1174 Y T G K W C E Y L T S I S F V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P10079 1064 112055 G740 N C A P G Y T G D N C E T E I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 58 96.4 N.A. 96.2 66.7 N.A. 91.2 93.3 87 79.6 N.A. 44.5 N.A. N.A. 20.2
Protein Similarity: 100 99.8 71.6 98.5 N.A. 98.4 81.3 N.A. 94.1 96.9 93.6 89.6 N.A. 63.5 N.A. N.A. 34.9
P-Site Identity: 100 93.3 0 100 N.A. 100 60 N.A. 80 80 46.6 53.3 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 93.3 0 100 N.A. 100 86.6 N.A. 86.6 86.6 73.3 66.6 N.A. 6.6 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 9 0 50 0 0 0 9 0 25 % A
% Cys: 0 9 0 0 0 9 0 0 0 0 9 0 0 0 0 % C
% Asp: 17 9 0 9 0 0 0 0 9 0 9 0 0 0 0 % D
% Glu: 59 0 0 0 9 0 9 0 0 0 0 9 9 9 0 % E
% Phe: 0 0 17 0 0 0 0 0 9 0 0 0 0 9 0 % F
% Gly: 0 0 9 0 9 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 9 0 67 0 0 0 0 25 9 0 0 9 % I
% Lys: 0 0 0 9 0 0 0 0 0 67 0 0 0 0 0 % K
% Leu: 0 0 0 59 0 9 17 0 9 9 9 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 9 9 0 0 0 9 0 % N
% Pro: 0 0 0 9 9 0 59 0 0 0 0 0 50 0 0 % P
% Gln: 0 0 0 0 59 0 0 9 0 0 0 0 9 75 0 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 50 0 0 0 % R
% Ser: 0 75 0 0 0 0 0 75 0 0 9 0 17 0 0 % S
% Thr: 0 9 0 0 9 0 9 0 17 17 0 9 9 0 50 % T
% Val: 9 0 0 9 0 0 0 0 0 0 42 0 0 0 9 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 9 % W
% Tyr: 9 0 59 0 0 17 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _