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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLIT2 All Species: 27.58
Human Site: S321 Identified Species: 55.15
UniProt: O94813 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94813 NP_004778.1 1529 169870 S321 V I P P G A F S P Y K K L R R
Chimpanzee Pan troglodytes XP_001163449 1529 169849 S321 V I P P G A F S P Y K K L R R
Rhesus Macaque Macaca mulatta XP_001094231 1706 186396 S505 S I P P G A F S P Y R K L R R
Dog Lupus familis XP_854843 1530 169605 S321 V I P P G A F S P Y K K L R R
Cat Felis silvestris
Mouse Mus musculus Q9R1B9 1521 168752 S321 V I P P G A F S P Y K K L R R
Rat Rattus norvegicus O88280 1523 167750 I328 S I P A G A F I Q Y K K L K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513256 1471 163510 Q277 R I D L S N N Q I S E A A P D
Chicken Gallus gallus XP_001232041 1528 169378 S320 V I P P G A F S P Y K K L R R
Frog Xenopus laevis NP_001081137 1530 170084 S330 V I P P G A F S P Y K K L R R
Zebra Danio Brachydanio rerio NP_571810 1512 166652 A312 I I P A G A F A P Y K R L R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24014 1504 168581 T343 S L T S V P V T L P D D T T E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P10079 1064 112055
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 58 96.4 N.A. 96.2 66.7 N.A. 91.2 93.3 87 79.6 N.A. 44.5 N.A. N.A. 20.2
Protein Similarity: 100 99.8 71.6 98.5 N.A. 98.4 81.3 N.A. 94.1 96.9 93.6 89.6 N.A. 63.5 N.A. N.A. 34.9
P-Site Identity: 100 100 86.6 100 N.A. 100 66.6 N.A. 6.6 100 100 73.3 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 100 N.A. 100 73.3 N.A. 13.3 100 100 93.3 N.A. 13.3 N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 0 75 0 9 0 0 0 9 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 9 9 0 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 84 0 0 0 0 0 9 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 67 67 0 9 0 % K
% Leu: 0 9 0 9 0 0 0 0 9 0 0 0 75 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 75 59 0 9 0 0 67 9 0 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 9 9 0 67 75 % R
% Ser: 25 0 0 9 9 0 0 59 0 9 0 0 0 0 0 % S
% Thr: 0 0 9 0 0 0 0 9 0 0 0 0 9 9 0 % T
% Val: 50 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 75 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _