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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLIT2
All Species:
34.24
Human Site:
Y1219
Identified Species:
68.48
UniProt:
O94813
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94813
NP_004778.1
1529
169870
Y1219
R
G
R
V
R
A
S
Y
D
T
G
S
H
P
A
Chimpanzee
Pan troglodytes
XP_001163449
1529
169849
Y1219
R
G
R
V
R
A
S
Y
D
T
G
S
H
P
A
Rhesus Macaque
Macaca mulatta
XP_001094231
1706
186396
T1397
A
G
M
V
Q
T
D
T
H
S
L
G
W
G
T
Dog
Lupus familis
XP_854843
1530
169605
Y1219
R
G
R
V
R
A
S
Y
D
T
G
S
H
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1B9
1521
168752
Y1211
R
G
R
V
R
A
S
Y
D
T
G
S
H
P
A
Rat
Rattus norvegicus
O88280
1523
167750
Y1217
Q
G
H
V
R
L
V
Y
D
S
L
S
S
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513256
1471
163510
Y1161
R
G
R
V
R
V
S
Y
D
T
G
S
Y
P
A
Chicken
Gallus gallus
XP_001232041
1528
169378
Y1218
R
G
R
V
R
V
S
Y
D
T
G
S
Y
P
A
Frog
Xenopus laevis
NP_001081137
1530
170084
Y1220
R
G
R
V
R
V
S
Y
D
T
G
S
N
P
S
Zebra Danio
Brachydanio rerio
NP_571810
1512
166652
Y1202
R
G
R
L
R
V
S
Y
D
S
G
S
Y
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24014
1504
168581
Q1218
G
I
L
M
Y
D
G
Q
D
A
H
L
A
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P10079
1064
112055
D784
T
G
V
I
C
E
T
D
I
D
E
C
A
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
58
96.4
N.A.
96.2
66.7
N.A.
91.2
93.3
87
79.6
N.A.
44.5
N.A.
N.A.
20.2
Protein Similarity:
100
99.8
71.6
98.5
N.A.
98.4
81.3
N.A.
94.1
96.9
93.6
89.6
N.A.
63.5
N.A.
N.A.
34.9
P-Site Identity:
100
100
13.3
100
N.A.
100
46.6
N.A.
86.6
86.6
80
66.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
26.6
100
N.A.
100
60
N.A.
93.3
93.3
93.3
86.6
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
34
0
0
0
9
0
0
17
0
59
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
9
9
9
84
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
92
0
0
0
0
9
0
0
0
67
9
0
9
0
% G
% His:
0
0
9
0
0
0
0
0
9
0
9
0
34
0
0
% H
% Ile:
0
9
0
9
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
9
0
9
0
0
0
0
17
9
0
0
0
% L
% Met:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
75
17
% P
% Gln:
9
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
67
0
67
0
75
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
67
0
0
25
0
75
9
9
9
% S
% Thr:
9
0
0
0
0
9
9
9
0
59
0
0
0
0
9
% T
% Val:
0
0
9
75
0
34
9
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
9
0
0
75
0
0
0
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _