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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLIT2
All Species:
18.18
Human Site:
Y444
Identified Species:
36.36
UniProt:
O94813
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94813
NP_004778.1
1529
169870
Y444
H
L
K
W
L
A
D
Y
L
H
T
N
P
I
E
Chimpanzee
Pan troglodytes
XP_001163449
1529
169849
Y444
H
L
K
W
L
A
D
Y
L
H
T
N
P
I
E
Rhesus Macaque
Macaca mulatta
XP_001094231
1706
186396
F628
N
L
K
W
L
A
D
F
L
R
T
N
P
I
E
Dog
Lupus familis
XP_854843
1530
169605
Y444
H
L
K
W
L
A
D
Y
L
H
T
N
P
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1B9
1521
168752
K439
F
I
C
D
C
H
L
K
W
L
A
D
Y
L
H
Rat
Rattus norvegicus
O88280
1523
167750
K446
F
V
C
D
C
H
L
K
W
L
A
D
Y
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513256
1471
163510
Y386
H
L
K
W
L
A
D
Y
L
H
T
N
P
I
E
Chicken
Gallus gallus
XP_001232041
1528
169378
Y443
H
L
K
W
L
A
D
Y
L
H
T
N
P
I
E
Frog
Xenopus laevis
NP_001081137
1530
170084
K448
F
I
C
D
C
H
L
K
W
L
A
D
Y
L
H
Zebra Danio
Brachydanio rerio
NP_571810
1512
166652
K430
F
M
C
D
C
H
L
K
W
L
A
D
Y
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24014
1504
168581
N452
S
L
L
S
L
Y
D
N
N
I
Q
S
L
A
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P10079
1064
112055
P79
M
I
D
S
P
N
Y
P
A
M
Y
N
N
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
58
96.4
N.A.
96.2
66.7
N.A.
91.2
93.3
87
79.6
N.A.
44.5
N.A.
N.A.
20.2
Protein Similarity:
100
99.8
71.6
98.5
N.A.
98.4
81.3
N.A.
94.1
96.9
93.6
89.6
N.A.
63.5
N.A.
N.A.
34.9
P-Site Identity:
100
100
80
100
N.A.
0
0
N.A.
100
100
0
0
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
20
26.6
N.A.
100
100
20
26.6
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
50
0
0
9
0
34
0
0
9
9
% A
% Cys:
0
0
34
0
34
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
34
0
0
59
0
0
0
0
34
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% E
% Phe:
34
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
42
0
0
0
0
34
0
0
0
42
0
0
0
0
17
% H
% Ile:
0
25
0
0
0
0
0
0
0
9
0
0
0
50
0
% I
% Lys:
0
0
50
0
0
0
0
34
0
0
0
0
0
0
0
% K
% Leu:
0
59
9
0
59
0
34
0
50
34
0
0
9
34
0
% L
% Met:
9
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
9
0
9
9
0
0
59
9
0
9
% N
% Pro:
0
0
0
0
9
0
0
9
0
0
0
0
50
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
17
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% R
% Ser:
9
0
0
17
0
0
0
0
0
0
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
50
0
0
0
0
34
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
9
42
0
0
9
0
34
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _