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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG12
All Species:
18.18
Human Site:
T118
Identified Species:
30.77
UniProt:
O94817
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94817
NP_004698.2
140
15113
T118
S
P
D
Q
E
V
G
T
L
Y
E
C
F
G
S
Chimpanzee
Pan troglodytes
XP_001167385
76
7989
I55
A
G
D
T
K
K
K
I
D
I
L
L
K
A
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531866
140
15054
T118
S
P
D
Q
E
V
G
T
L
Y
E
C
F
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQY1
141
15189
T119
S
P
D
Q
E
V
G
T
L
Y
E
C
F
G
S
Rat
Rattus norvegicus
Q2TBJ5
141
15265
T119
S
P
D
Q
E
V
G
T
L
Y
E
C
F
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516790
74
8509
R53
K
W
A
V
E
R
T
R
T
I
Q
G
L
I
D
Chicken
Gallus gallus
XP_424963
146
15559
T124
S
P
D
Q
E
V
G
T
L
Y
E
C
F
G
S
Frog
Xenopus laevis
NP_001104222
132
14584
L111
P
D
Q
E
V
G
T
L
Y
E
C
F
G
S
D
Zebra Danio
Brachydanio rerio
XP_699602
120
13594
V98
S
P
D
Q
E
V
G
V
L
F
E
C
F
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU1
111
12330
L90
P
D
Q
I
I
K
N
L
Y
E
C
H
G
T
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787754
126
13936
L105
P
D
Q
E
I
R
N
L
F
E
C
Y
G
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVK3
94
10339
L73
P
D
E
S
V
I
D
L
Y
N
N
F
G
F
D
Baker's Yeast
Sacchar. cerevisiae
P38316
186
21087
E164
S
P
Q
Q
N
I
G
E
L
W
M
Q
F
K
T
Red Bread Mold
Neurospora crassa
Q7S083
157
16983
N134
A
L
D
E
V
V
G
N
L
W
R
C
F
K
D
Conservation
Percent
Protein Identity:
100
48.5
N.A.
92.8
N.A.
88.6
85.1
N.A.
40.7
74.6
67.1
62.8
N.A.
49.2
N.A.
N.A.
48.5
Protein Similarity:
100
50
N.A.
95
N.A.
92.9
91.4
N.A.
42.1
80.1
77.8
70
N.A.
64.2
N.A.
N.A.
62.1
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
6.6
100
0
86.6
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
20
N.A.
100
N.A.
100
100
N.A.
13.3
100
6.6
93.3
N.A.
6.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.2
22.5
26.7
Protein Similarity:
N.A.
N.A.
N.A.
47.8
43
49.6
P-Site Identity:
N.A.
N.A.
N.A.
0
40
40
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
60
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
22
50
0
0
0
% C
% Asp:
0
29
58
0
0
0
8
0
8
0
0
0
0
0
36
% D
% Glu:
0
0
8
22
50
0
0
8
0
22
43
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
0
15
58
8
0
% F
% Gly:
0
8
0
0
0
8
58
0
0
0
0
8
29
43
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
8
15
15
0
8
0
15
0
0
0
8
0
% I
% Lys:
8
0
0
0
8
15
8
0
0
0
0
0
8
15
0
% K
% Leu:
0
8
0
0
0
0
0
29
58
0
8
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
15
8
0
8
8
0
0
0
8
% N
% Pro:
29
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
29
50
0
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
0
0
0
0
0
15
0
8
0
0
8
0
0
0
0
% R
% Ser:
50
0
0
8
0
0
0
0
0
0
0
0
0
15
43
% S
% Thr:
0
0
0
8
0
0
15
36
8
0
0
0
0
8
8
% T
% Val:
0
0
0
8
22
50
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
8
0
0
0
0
0
0
0
15
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
22
36
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _