Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG12 All Species: 12.42
Human Site: T31 Identified Species: 21.03
UniProt: O94817 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94817 NP_004698.2 140 15113 T31 D V S P E T T T P E P P S S A
Chimpanzee Pan troglodytes XP_001167385 76 7989
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531866 140 15054 T31 E V S P E T A T P E P P S S A
Cat Felis silvestris
Mouse Mus musculus Q9CQY1 141 15189 T32 E L S P E T A T P E P P S S A
Rat Rattus norvegicus Q2TBJ5 141 15265 I32 E L S P E T A I P E P P S S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516790 74 8509
Chicken Gallus gallus XP_424963 146 15559 V37 E S G A S L G V G E P A T S P
Frog Xenopus laevis NP_001104222 132 14584 T26 N A E T P P E T A P A P V V S
Zebra Danio Brachydanio rerio XP_699602 120 13594 P12 A E S P T E N P K D E H S L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VTU1 111 12330
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787754 126 13936 Q20 E T A D P G T Q N D Q I S K Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVK3 94 10339
Baker's Yeast Sacchar. cerevisiae P38316 186 21087 Y77 E D S S S G T Y E Q E E T I K
Red Bread Mold Neurospora crassa Q7S083 157 16983 T47 P L T M T A S T V L M T L P R
Conservation
Percent
Protein Identity: 100 48.5 N.A. 92.8 N.A. 88.6 85.1 N.A. 40.7 74.6 67.1 62.8 N.A. 49.2 N.A. N.A. 48.5
Protein Similarity: 100 50 N.A. 95 N.A. 92.9 91.4 N.A. 42.1 80.1 77.8 70 N.A. 64.2 N.A. N.A. 62.1
P-Site Identity: 100 0 N.A. 86.6 N.A. 80 66.6 N.A. 0 20 13.3 20 N.A. 0 N.A. N.A. 13.3
P-Site Similarity: 100 0 N.A. 93.3 N.A. 93.3 80 N.A. 0 33.3 26.6 26.6 N.A. 0 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 34.2 22.5 26.7
Protein Similarity: N.A. N.A. N.A. 47.8 43 49.6
P-Site Identity: N.A. N.A. N.A. 0 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 0 33.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 8 0 8 22 0 8 0 8 8 0 0 22 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 8 0 0 0 0 0 15 0 0 0 0 0 % D
% Glu: 43 8 8 0 29 8 8 0 8 36 15 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 15 8 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 8 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 8 % K
% Leu: 0 22 0 0 0 8 0 0 0 8 0 0 8 8 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % N
% Pro: 8 0 0 36 15 8 0 8 29 8 36 36 0 8 8 % P
% Gln: 0 0 0 0 0 0 0 8 0 8 8 0 0 0 15 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 0 8 43 8 15 0 8 0 0 0 0 0 43 36 8 % S
% Thr: 0 8 8 8 15 29 22 36 0 0 0 8 15 0 0 % T
% Val: 0 15 0 0 0 0 0 8 8 0 0 0 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _