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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP10B All Species: 8.18
Human Site: T645 Identified Species: 16.36
UniProt: O94823 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94823 NP_079429.2 1461 165391 T645 S S T A P S D T D L G E S L G
Chimpanzee Pan troglodytes XP_001137552 1891 213106 T721 S S T A P S D T D L G E S L G
Rhesus Macaque Macaca mulatta XP_001086695 1389 157289 L604 A A L W L E T L S E S R P A K
Dog Lupus familis XP_546266 1476 167459 I657 S S T A P S D I D L G E S L G
Cat Felis silvestris
Mouse Mus musculus Q8K2X1 1416 158311 R635 F Q K L S V R R S S S P S L A
Rat Rattus norvegicus XP_001067759 1472 165828 D645 S T A P S D T D L G E S L G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505859 1477 166976 T646 S S T A S G E T D L G A Q E R
Chicken Gallus gallus XP_420722 1419 160505 S637 L P S I K E S S S E N P S S F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_692383 1302 148318 D522 R E T V V V P D R K L M L E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392716 1473 164940 L663 R Q H L Q E F L I V L A I C N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P98204 1158 130310 K377 Y S E R P G G K N Y K Y Y G W
Baker's Yeast Sacchar. cerevisiae P39524 1355 153826 C575 N I M E F K S C S I A G H C Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 88.5 85 N.A. 50.8 83.4 N.A. 68.1 50.5 N.A. 49.9 N.A. N.A. 28.5 N.A. N.A.
Protein Similarity: 100 76.4 89.7 90.3 N.A. 66.3 89.9 N.A. 79.4 67.4 N.A. 65.7 N.A. N.A. 46.2 N.A. N.A.
P-Site Identity: 100 100 0 93.3 N.A. 13.3 6.6 N.A. 53.3 6.6 N.A. 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 13.3 13.3 N.A. 60 20 N.A. 6.6 N.A. N.A. 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.7 24.7 N.A.
Protein Similarity: N.A. N.A. N.A. 50.1 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 9 34 0 0 0 0 0 0 9 17 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 17 0 % C
% Asp: 0 0 0 0 0 9 25 17 34 0 0 0 0 0 0 % D
% Glu: 0 9 9 9 0 25 9 0 0 17 9 25 0 17 0 % E
% Phe: 9 0 0 0 9 0 9 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 17 9 0 0 9 34 9 0 17 25 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 0 9 0 0 0 9 9 9 0 0 9 0 0 % I
% Lys: 0 0 9 0 9 9 0 9 0 9 9 0 0 0 9 % K
% Leu: 9 0 9 17 9 0 0 17 9 34 17 0 17 34 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 9 0 9 0 0 0 9 % N
% Pro: 0 9 0 9 34 0 9 0 0 0 0 17 9 0 9 % P
% Gln: 0 17 0 0 9 0 0 0 0 0 0 0 9 0 0 % Q
% Arg: 17 0 0 9 0 0 9 9 9 0 0 9 0 0 9 % R
% Ser: 42 42 9 0 25 25 17 9 34 9 17 9 42 9 0 % S
% Thr: 0 9 42 0 0 0 17 25 0 0 0 0 0 0 0 % T
% Val: 0 0 0 9 9 17 0 0 0 9 0 0 0 0 9 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 9 0 0 0 0 0 0 0 0 9 0 9 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _