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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG5
All Species:
4.55
Human Site:
S609
Identified Species:
11.11
UniProt:
O94827
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94827
NP_001036128.1
1062
117451
S609
D
A
Y
E
V
V
E
S
S
S
D
E
V
D
K
Chimpanzee
Pan troglodytes
XP_514339
811
89180
V383
W
A
S
V
M
A
P
V
L
E
K
A
R
R
T
Rhesus Macaque
Macaca mulatta
XP_001092760
1078
119138
S629
D
A
Y
E
V
V
E
S
S
S
D
E
V
D
K
Dog
Lupus familis
XP_536728
1103
122800
G645
D
A
Y
E
V
V
E
G
S
N
D
E
V
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q66T02
1073
118906
G623
D
A
Y
E
V
V
E
G
S
N
D
E
V
D
K
Rat
Rattus norvegicus
Q6RFZ7
1039
115766
G589
D
A
Y
E
V
V
E
G
S
N
D
E
V
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518326
472
55138
L44
E
D
E
E
D
T
D
L
C
L
E
D
S
W
Q
Chicken
Gallus gallus
XP_423692
451
48811
R23
M
L
V
K
P
H
Q
R
L
T
K
Y
P
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923813
860
97118
Q432
E
K
V
K
V
I
R
Q
P
L
V
I
H
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392491
767
84898
K339
Q
K
D
C
N
R
L
K
L
L
D
I
L
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.1
94.3
85.3
N.A.
82.1
83.1
N.A.
37.7
27
N.A.
37.6
N.A.
N.A.
26.5
N.A.
N.A.
Protein Similarity:
100
73.1
95.7
88.7
N.A.
86.6
87.6
N.A.
41.3
31.6
N.A.
49.9
N.A.
N.A.
41.3
N.A.
N.A.
P-Site Identity:
100
6.6
100
86.6
N.A.
86.6
86.6
N.A.
6.6
0
N.A.
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
13.3
100
93.3
N.A.
93.3
93.3
N.A.
40
20
N.A.
33.3
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
0
0
10
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
50
10
10
0
10
0
10
0
0
0
60
10
0
50
0
% D
% Glu:
20
0
10
60
0
0
50
0
0
10
10
50
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
20
0
0
0
% I
% Lys:
0
20
0
20
0
0
0
10
0
0
20
0
0
0
60
% K
% Leu:
0
10
0
0
0
0
10
10
30
30
0
0
10
10
10
% L
% Met:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
30
0
0
0
10
0
% N
% Pro:
0
0
0
0
10
0
10
0
10
0
0
0
10
0
0
% P
% Gln:
10
0
0
0
0
0
10
10
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
10
10
10
0
0
0
0
10
10
0
% R
% Ser:
0
0
10
0
0
0
0
20
50
20
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% T
% Val:
0
0
20
10
60
50
0
10
0
0
10
0
50
10
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
50
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _