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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG5
All Species:
18.18
Human Site:
Y875
Identified Species:
44.44
UniProt:
O94827
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94827
NP_001036128.1
1062
117451
Y875
S
C
S
M
D
S
A
Y
G
T
L
S
P
T
S
Chimpanzee
Pan troglodytes
XP_514339
811
89180
H630
S
S
S
P
D
S
Q
H
C
A
S
D
G
S
T
Rhesus Macaque
Macaca mulatta
XP_001092760
1078
119138
Y893
S
C
S
M
D
S
A
Y
G
T
L
S
P
T
S
Dog
Lupus familis
XP_536728
1103
122800
Y913
S
C
S
M
D
S
A
Y
G
T
L
S
P
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q66T02
1073
118906
Y883
S
C
S
M
D
S
A
Y
G
T
L
S
P
T
S
Rat
Rattus norvegicus
Q6RFZ7
1039
115766
Y850
S
C
S
M
D
S
A
Y
G
T
L
S
P
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518326
472
55138
L291
S
T
D
E
V
D
K
L
L
K
E
F
L
R
L
Chicken
Gallus gallus
XP_423692
451
48811
D270
S
C
C
S
A
S
I
D
S
A
Y
G
T
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923813
860
97118
L679
L
D
T
N
S
E
E
L
N
R
R
N
D
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392491
767
84898
L586
N
R
Q
H
S
S
F
L
G
D
E
Y
E
A
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.1
94.3
85.3
N.A.
82.1
83.1
N.A.
37.7
27
N.A.
37.6
N.A.
N.A.
26.5
N.A.
N.A.
Protein Similarity:
100
73.1
95.7
88.7
N.A.
86.6
87.6
N.A.
41.3
31.6
N.A.
49.9
N.A.
N.A.
41.3
N.A.
N.A.
P-Site Identity:
100
26.6
100
100
N.A.
100
100
N.A.
6.6
26.6
N.A.
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
46.6
100
100
N.A.
100
100
N.A.
6.6
26.6
N.A.
20
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
50
0
0
20
0
0
0
10
0
% A
% Cys:
0
60
10
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
60
10
0
10
0
10
0
10
10
0
0
% D
% Glu:
0
0
0
10
0
10
10
0
0
0
20
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
10
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
60
0
0
10
10
0
0
% G
% His:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
30
10
0
50
0
10
10
10
% L
% Met:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
50
0
0
% P
% Gln:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
10
10
0
0
10
0
% R
% Ser:
80
10
60
10
20
80
0
0
10
0
10
50
0
10
70
% S
% Thr:
0
10
10
0
0
0
0
0
0
50
0
0
10
50
10
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _