KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1D
All Species:
20.3
Human Site:
S218
Identified Species:
37.22
UniProt:
O94832
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94832
NP_056009.1
1006
116202
S218
G
S
E
Q
M
L
R
S
L
H
L
Q
K
S
L
Chimpanzee
Pan troglodytes
XP_511404
1147
131183
S359
G
S
E
Q
M
L
R
S
L
H
L
Q
K
S
L
Rhesus Macaque
Macaca mulatta
XP_001110356
1064
122506
Q220
A
Q
S
R
V
I
V
Q
Q
P
G
E
R
S
F
Dog
Lupus familis
XP_548273
1132
129358
S344
G
S
E
Q
M
L
R
S
L
H
L
Q
K
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5SYD0
1006
116063
S218
G
S
E
Q
M
L
H
S
L
H
L
Q
K
S
L
Rat
Rattus norvegicus
Q63357
1006
116077
S218
G
S
E
Q
M
L
H
S
L
H
L
Q
K
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMC2
1007
114951
S218
A
P
D
A
L
L
A
S
L
H
L
Q
R
D
P
Frog
Xenopus laevis
A0MP03
1028
118817
R219
G
E
E
E
L
L
R
R
L
G
L
D
K
N
A
Zebra Danio
Brachydanio rerio
A5PF48
1026
118045
R219
G
E
D
L
L
L
K
R
L
G
L
D
K
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23978
1011
117077
Q216
A
N
D
N
E
L
R
Q
Y
E
L
Q
K
E
T
Honey Bee
Apis mellifera
XP_624678
1017
118012
K216
C
S
E
G
E
L
N
K
L
R
L
V
R
D
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780215
1017
117582
E218
C
T
E
Q
I
L
K
E
F
K
L
K
R
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
M249
A
S
Q
Q
Y
R
E
M
Y
G
I
Q
K
P
E
Conservation
Percent
Protein Identity:
100
87.3
82.7
87.4
N.A.
97.7
98
N.A.
N.A.
64.9
40.2
40.3
N.A.
53.9
54.8
N.A.
56.7
Protein Similarity:
100
87.5
85.3
88.2
N.A.
99.1
99.3
N.A.
N.A.
80.2
58.6
58.4
N.A.
70.3
71.4
N.A.
74.1
P-Site Identity:
100
100
6.6
100
N.A.
93.3
93.3
N.A.
N.A.
40
46.6
33.3
N.A.
33.3
33.3
N.A.
26.6
P-Site Similarity:
100
100
40
100
N.A.
93.3
93.3
N.A.
N.A.
60
66.6
60
N.A.
46.6
40
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% A
% Cys:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
24
0
0
0
0
0
0
0
0
16
0
24
0
% D
% Glu:
0
16
62
8
16
0
8
8
0
8
0
8
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
54
0
0
8
0
0
0
0
0
24
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
16
0
0
47
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
16
8
0
8
0
8
70
0
0
% K
% Leu:
0
0
0
8
24
85
0
0
70
0
85
0
0
0
39
% L
% Met:
0
0
0
0
39
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
8
0
0
0
0
0
0
8
8
% N
% Pro:
0
8
0
0
0
0
0
0
0
8
0
0
0
8
24
% P
% Gln:
0
8
8
54
0
0
0
16
8
0
0
62
0
0
0
% Q
% Arg:
0
0
0
8
0
8
39
16
0
8
0
0
31
0
0
% R
% Ser:
0
54
8
0
0
0
0
47
0
0
0
0
0
47
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% T
% Val:
0
0
0
0
8
0
8
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
16
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _