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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOX4
All Species:
21.82
Human Site:
S117
Identified Species:
60
UniProt:
O94842
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94842
NP_055643.1
621
66195
S117
H
S
I
G
T
Q
Y
S
A
N
P
P
V
T
I
Chimpanzee
Pan troglodytes
XP_510963
590
64823
R120
L
P
S
I
T
I
S
R
N
L
V
E
Q
D
G
Rhesus Macaque
Macaca mulatta
NP_001165884
621
66180
S117
H
S
I
G
T
Q
Y
S
A
N
P
P
V
T
I
Dog
Lupus familis
XP_532626
619
66076
S117
H
S
I
G
T
Q
Y
S
A
N
P
P
V
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU11
619
65973
S117
H
S
I
G
T
Q
Y
S
A
N
P
P
V
T
I
Rat
Rattus norvegicus
Q99PM1
619
65991
S117
H
S
I
G
T
Q
Y
S
A
N
P
P
V
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520125
610
67306
P142
P
Q
G
N
E
F
T
P
Q
F
P
P
Q
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6IRR0
594
63660
S117
H
P
I
V
T
P
Y
S
A
N
P
P
V
T
I
Zebra Danio
Brachydanio rerio
NP_001121758
583
61470
L117
L
L
T
S
T
L
D
L
G
H
P
I
G
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.9
99.8
97.5
N.A.
95.1
94.3
N.A.
38.1
N.A.
64.2
50.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
56.2
99.8
98.3
N.A.
97
96.1
N.A.
55.8
N.A.
73.5
62.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
13.3
N.A.
80
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
26.6
N.A.
80
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
0
12
56
0
0
0
0
12
0
0
0
12
0
12
% G
% His:
67
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
67
12
0
12
0
0
0
0
0
12
0
0
67
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
23
12
0
0
0
12
0
12
0
12
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
12
67
0
0
0
0
0
% N
% Pro:
12
23
0
0
0
12
0
12
0
0
89
78
0
0
0
% P
% Gln:
0
12
0
0
0
56
0
0
12
0
0
0
23
0
12
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
56
12
12
0
0
12
67
0
0
0
0
0
23
0
% S
% Thr:
0
0
12
0
89
0
12
0
0
0
0
0
0
67
0
% T
% Val:
0
0
0
12
0
0
0
0
0
0
12
0
67
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _