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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0754 All Species: 4.55
Human Site: Y537 Identified Species: 20
UniProt: O94854 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94854 NP_055853.1 1291 135147 Y537 G P E V E V L Y E S N L L T D
Chimpanzee Pan troglodytes XP_001170899 1363 144271 Y673 G P E V E V L Y E S N L L T D
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q69ZZ9 979 104621 L308 L E G L T S G L Q C P V E A E
Rat Rattus norvegicus P16884 1072 115359 L401 E I A A Y R K L L E G E E C R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P16053 858 95817 D186 R L R E R F E D E A R L R D E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611285 485 50527
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.8 N.A. N.A. N.A. 51.7 21.4 N.A. N.A. 23 N.A. N.A. N.A. 21.6 N.A. N.A. N.A.
Protein Similarity: 100 89.2 N.A. N.A. N.A. 60.1 35.4 N.A. N.A. 36.9 N.A. N.A. N.A. 28.2 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. N.A. N.A. 0 0 N.A. N.A. 13.3 N.A. N.A. N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. N.A. N.A. 26.6 0 N.A. N.A. 26.6 N.A. N.A. N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 17 0 0 0 0 0 17 0 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 17 0 0 0 17 0 % C
% Asp: 0 0 0 0 0 0 0 17 0 0 0 0 0 17 34 % D
% Glu: 17 17 34 17 34 0 17 0 50 17 0 17 34 0 34 % E
% Phe: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % F
% Gly: 34 0 17 0 0 0 17 0 0 0 17 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % K
% Leu: 17 17 0 17 0 0 34 34 17 0 0 50 34 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % N
% Pro: 0 34 0 0 0 0 0 0 0 0 17 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % Q
% Arg: 17 0 17 0 17 17 0 0 0 0 17 0 17 0 17 % R
% Ser: 0 0 0 0 0 17 0 0 0 34 0 0 0 0 0 % S
% Thr: 0 0 0 0 17 0 0 0 0 0 0 0 0 34 0 % T
% Val: 0 0 0 34 0 34 0 0 0 0 0 17 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 17 0 0 34 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _