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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24D All Species: 8.79
Human Site: S116 Identified Species: 14.87
UniProt: O94855 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94855 NP_055637.2 1032 113010 S116 P G P I S T S S V T Q L G S Q
Chimpanzee Pan troglodytes XP_001145058 1094 118246 A167 F G P P T S L A S A S G S F P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535702 1171 127156 S259 P S P A S T S S V T Q L G N Q
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 N150 P S T G P Q T N H F P H V A P
Rat Rattus norvegicus NP_001102926 1095 118506 T181 P N S G P Y S T Y P Q S Q A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513076 1029 112278 S117 S S S S S S S S T T Q L G H Q
Chicken Gallus gallus XP_420635 1038 113834 C126 P H T A S T S C T T Q L A N Q
Frog Xenopus laevis NP_001087832 1126 123503 S202 P P T S L P Q S Q P T Q Q R F
Zebra Danio Brachydanio rerio XP_700597 1315 142554 A227 T F P P T S S A P S Q P P P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 N264 L P G Q N F S N P I I S G Q P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 P220 G G Y G A G P P S S Q A P P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M291 1097 117779 F126 P P S N Q P P F G G R P S T G
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 V91 H L H N V P L V D P N A Y M Q
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 A105 A Q D A Q Q V A Y G A P T T P
Conservation
Percent
Protein Identity: 100 55.6 N.A. 81 N.A. 26.9 55.4 N.A. 76.1 75.3 54.3 49.9 N.A. N.A. 41.3 N.A. 47.6
Protein Similarity: 100 70.8 N.A. 83.5 N.A. 44.4 70.5 N.A. 85.3 84.9 69.3 61.6 N.A. N.A. 56.8 N.A. 63.1
P-Site Identity: 100 13.3 N.A. 80 N.A. 6.6 20 N.A. 53.3 53.3 13.3 20 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 33.3 N.A. 86.6 N.A. 26.6 33.3 N.A. 60 60 13.3 46.6 N.A. N.A. 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 32.4 27.2 28
Protein Similarity: N.A. N.A. N.A. 50.5 44.3 47.2
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 0
P-Site Similarity: N.A. N.A. N.A. 20 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 22 8 0 0 22 0 8 8 15 8 15 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 8 0 0 0 8 0 8 0 8 0 0 0 8 8 % F
% Gly: 8 22 8 22 0 8 0 0 8 15 0 8 29 0 8 % G
% His: 8 8 8 0 0 0 0 0 8 0 0 8 0 8 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 8 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 8 0 0 8 0 15 0 0 0 0 29 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 8 0 15 8 0 0 15 0 0 8 0 0 15 0 % N
% Pro: 50 22 29 15 15 22 15 8 15 22 8 22 15 15 36 % P
% Gln: 0 8 0 8 15 15 8 0 8 0 50 8 15 8 36 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % R
% Ser: 8 22 22 15 29 22 50 29 15 15 8 15 15 8 8 % S
% Thr: 8 0 22 0 15 22 8 8 15 29 8 0 8 15 8 % T
% Val: 0 0 0 0 8 0 8 8 15 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 8 0 0 15 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _