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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24D All Species: 14.55
Human Site: S131 Identified Species: 24.62
UniProt: O94855 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94855 NP_055637.2 1032 113010 S131 L S A M Q I N S Y G S G M A P
Chimpanzee Pan troglodytes XP_001145058 1094 118246 Y182 N S G L Y G S Y P Q G Q A P P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535702 1171 127156 S274 F N A M H I N S Y G S G M A A
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 N165 P T L P G N P N L T A D H Q Y
Rat Rattus norvegicus NP_001102926 1095 118506 H196 P L S Q A Q G H P G V Q P P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513076 1029 112278 S132 L S A M H I N S Y G P G M A P
Chicken Gallus gallus XP_420635 1038 113834 S141 L N S M Q I N S Y G P S A I Q
Frog Xenopus laevis NP_001087832 1126 123503 N217 A S G P P P Q N L P S S Q A P
Zebra Danio Brachydanio rerio XP_700597 1315 142554 P242 E A V A Q P P P L P Y Y G A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 S279 N L S G P P L S N Q Q T H K D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 T235 G F Q G Q P P T G F A S G P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M291 1097 117779 S141 P L V G G G S S F P Q P G G F
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 G106 P Q V P V Q M G T P L Q Q Q Q
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 V120 Y G A P Q P A V P G V G G Y Q
Conservation
Percent
Protein Identity: 100 55.6 N.A. 81 N.A. 26.9 55.4 N.A. 76.1 75.3 54.3 49.9 N.A. N.A. 41.3 N.A. 47.6
Protein Similarity: 100 70.8 N.A. 83.5 N.A. 44.4 70.5 N.A. 85.3 84.9 69.3 61.6 N.A. N.A. 56.8 N.A. 63.1
P-Site Identity: 100 13.3 N.A. 73.3 N.A. 0 6.6 N.A. 86.6 53.3 26.6 20 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 26.6 N.A. 80 N.A. 20 13.3 N.A. 86.6 66.6 33.3 26.6 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 32.4 27.2 28
Protein Similarity: N.A. N.A. N.A. 50.5 44.3 47.2
P-Site Identity: N.A. N.A. N.A. 6.6 0 26.6
P-Site Similarity: N.A. N.A. N.A. 20 0 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 29 8 8 0 8 0 0 0 15 0 15 36 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 8 0 0 0 0 0 0 8 8 0 0 0 0 8 % F
% Gly: 8 8 15 22 15 15 8 8 8 43 8 29 29 8 0 % G
% His: 0 0 0 0 15 0 0 8 0 0 0 0 15 0 0 % H
% Ile: 0 0 0 0 0 29 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % K
% Leu: 22 22 8 8 0 0 8 0 22 0 8 0 0 0 8 % L
% Met: 0 0 0 29 0 0 8 0 0 0 0 0 22 0 0 % M
% Asn: 15 15 0 0 0 8 29 15 8 0 0 0 0 0 0 % N
% Pro: 29 0 0 29 15 36 22 8 22 29 15 8 8 22 43 % P
% Gln: 0 8 8 8 36 15 8 0 0 15 15 22 15 15 22 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 29 22 0 0 0 15 43 0 0 22 22 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 8 8 8 0 8 0 0 0 % T
% Val: 0 0 22 0 8 0 0 8 0 0 15 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 0 0 8 29 0 8 8 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _