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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24D All Species: 32.73
Human Site: S266 Identified Species: 55.38
UniProt: O94855 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94855 NP_055637.2 1032 113010 S266 L D P D S I P S P I Q V I E N
Chimpanzee Pan troglodytes XP_001145058 1094 118246 S328 L D P D A I P S P I Q V I E D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535702 1171 127156 S405 L D P D S I P S P I Q V I E N
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 S292 S V G S A Y P S L P P G Y Q N
Rat Rattus norvegicus NP_001102926 1095 118506 S329 L D P D A I P S P I Q V I E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513076 1029 112278 S267 L D P D S I P S P I Q V I E N
Chicken Gallus gallus XP_420635 1038 113834 S272 L D P D S I P S P I Q V I E N
Frog Xenopus laevis NP_001087832 1126 123503 P360 R L D P D S I P S P I Q V I E
Zebra Danio Brachydanio rerio XP_700597 1315 142554 S527 L D P D S I P S P I Q V I E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 P509 R L D P E Q M P S P I Q V I Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 S384 L D P D Q M P S A I Q V I D D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M291 1097 117779 L337 S S P S K I D L N Q I P R P G
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 C231 E D G L I V R C R R C R S Y M
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 P245 L L K K S K L P F A L V I Q P
Conservation
Percent
Protein Identity: 100 55.6 N.A. 81 N.A. 26.9 55.4 N.A. 76.1 75.3 54.3 49.9 N.A. N.A. 41.3 N.A. 47.6
Protein Similarity: 100 70.8 N.A. 83.5 N.A. 44.4 70.5 N.A. 85.3 84.9 69.3 61.6 N.A. N.A. 56.8 N.A. 63.1
P-Site Identity: 100 86.6 N.A. 100 N.A. 20 86.6 N.A. 100 100 0 93.3 N.A. N.A. 0 N.A. 66.6
P-Site Similarity: 100 100 N.A. 100 N.A. 33.3 100 N.A. 100 100 6.6 100 N.A. N.A. 6.6 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. 32.4 27.2 28
Protein Similarity: N.A. N.A. N.A. 50.5 44.3 47.2
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 26.6
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 22 0 0 0 8 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % C
% Asp: 0 65 15 58 8 0 8 0 0 0 0 0 0 8 29 % D
% Glu: 8 0 0 0 8 0 0 0 0 0 0 0 0 50 8 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 15 0 0 0 0 0 0 0 0 8 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 58 8 0 0 58 22 0 65 15 0 % I
% Lys: 0 0 8 8 8 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 65 22 0 8 0 0 8 8 8 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 36 % N
% Pro: 0 0 65 15 0 0 65 22 50 22 8 8 0 8 8 % P
% Gln: 0 0 0 0 8 8 0 0 0 8 58 15 0 15 8 % Q
% Arg: 15 0 0 0 0 0 8 0 8 8 0 8 8 0 0 % R
% Ser: 15 8 0 15 43 8 0 65 15 0 0 0 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 8 0 0 0 8 0 0 0 0 0 65 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _