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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC24D
All Species:
34.55
Human Site:
S418
Identified Species:
58.46
UniProt:
O94855
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94855
NP_055637.2
1032
113010
S418
H
Y
E
K
P
E
L
S
L
G
S
Y
E
Y
V
Chimpanzee
Pan troglodytes
XP_001145058
1094
118246
S480
A
Y
D
R
P
E
L
S
L
G
S
Y
E
F
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535702
1171
127156
S557
H
Y
E
K
P
E
L
S
L
G
S
Y
E
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2P1
1090
118764
V455
K
C
N
L
C
Y
R
V
N
D
V
P
E
E
F
Rat
Rattus norvegicus
NP_001102926
1095
118506
S481
A
Y
D
R
P
E
L
S
L
G
S
Y
E
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513076
1029
112278
S419
H
Y
E
K
P
E
L
S
L
G
S
Y
E
F
V
Chicken
Gallus gallus
XP_420635
1038
113834
S424
H
Y
E
R
P
E
L
S
L
G
S
Y
E
Y
V
Frog
Xenopus laevis
NP_001087832
1126
123503
S512
C
Y
E
R
P
E
L
S
M
G
S
Y
E
F
T
Zebra Danio
Brachydanio rerio
XP_700597
1315
142554
S679
C
Y
E
R
P
E
L
S
M
G
S
Y
E
F
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392952
1276
140829
M661
R
Y
E
R
P
E
L
M
L
G
T
Y
E
Y
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783728
1150
123558
S536
M
F
E
R
P
E
L
S
L
G
T
F
E
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M291
1097
117779
C489
A
D
E
R
P
E
L
C
R
G
T
V
D
F
V
Baker's Yeast
Sacchar. cerevisiae
P40482
926
103617
A379
Q
I
N
M
M
D
I
A
D
L
E
E
P
F
L
Red Bread Mold
Neurospora crassa
Q7S4P3
950
103512
A393
R
T
R
L
G
F
I
A
V
D
S
S
L
H
Y
Conservation
Percent
Protein Identity:
100
55.6
N.A.
81
N.A.
26.9
55.4
N.A.
76.1
75.3
54.3
49.9
N.A.
N.A.
41.3
N.A.
47.6
Protein Similarity:
100
70.8
N.A.
83.5
N.A.
44.4
70.5
N.A.
85.3
84.9
69.3
61.6
N.A.
N.A.
56.8
N.A.
63.1
P-Site Identity:
100
66.6
N.A.
100
N.A.
6.6
66.6
N.A.
93.3
93.3
66.6
66.6
N.A.
N.A.
66.6
N.A.
53.3
P-Site Similarity:
100
93.3
N.A.
100
N.A.
6.6
93.3
N.A.
100
100
86.6
93.3
N.A.
N.A.
86.6
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.4
27.2
28
Protein Similarity:
N.A.
N.A.
N.A.
50.5
44.3
47.2
P-Site Identity:
N.A.
N.A.
N.A.
40
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% A
% Cys:
15
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
15
0
0
8
0
0
8
15
0
0
8
0
0
% D
% Glu:
0
0
65
0
0
79
0
0
0
0
8
8
79
8
0
% E
% Phe:
0
8
0
0
0
8
0
0
0
0
0
8
0
58
8
% F
% Gly:
0
0
0
0
8
0
0
0
0
79
0
0
0
0
0
% G
% His:
29
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
0
15
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
15
0
0
79
0
58
8
0
0
8
0
29
% L
% Met:
8
0
0
8
8
0
0
8
15
0
0
0
0
0
8
% M
% Asn:
0
0
15
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
79
0
0
0
0
0
0
8
8
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
0
8
58
0
0
8
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
65
0
0
65
8
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
22
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
8
8
0
8
8
0
0
36
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
65
0
0
0
8
0
0
0
0
0
65
0
29
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _