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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24D All Species: 1.52
Human Site: S434 Identified Species: 2.56
UniProt: O94855 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94855 NP_055637.2 1032 113010 S434 T L D Y C R K S K P P N P P A
Chimpanzee Pan troglodytes XP_001145058 1094 118246 N496 T V D Y C K N N K F P S P P A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535702 1171 127156 N573 T L D Y C R K N K P P N P P A
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 Y471 Y N P L T R V Y G E P H K R P
Rat Rattus norvegicus NP_001102926 1095 118506 N497 T V D Y C K N N K F P S P P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513076 1029 112278 N435 T L D Y C R N N T P P N P P A
Chicken Gallus gallus XP_420635 1038 113834 N440 T L D Y C R N N K P P N P P A
Frog Xenopus laevis NP_001087832 1126 123503 N528 T V D Y C K N N K I P N P P A
Zebra Danio Brachydanio rerio XP_700597 1315 142554 N695 T V D Y C K N N K F P Q P P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 N677 T K D Y C R N N T F P K P P A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 N552 T T D Y C K N N T P P K P P A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M291 1097 117779 D505 T K E Y M V R D P M P A V Y F
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 S395 R P N S M V V S L K A C R Q N
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 E409 S V P R D T E E N G E T S M L
Conservation
Percent
Protein Identity: 100 55.6 N.A. 81 N.A. 26.9 55.4 N.A. 76.1 75.3 54.3 49.9 N.A. N.A. 41.3 N.A. 47.6
Protein Similarity: 100 70.8 N.A. 83.5 N.A. 44.4 70.5 N.A. 85.3 84.9 69.3 61.6 N.A. N.A. 56.8 N.A. 63.1
P-Site Identity: 100 60 N.A. 93.3 N.A. 13.3 60 N.A. 80 86.6 66.6 60 N.A. N.A. 60 N.A. 60
P-Site Similarity: 100 86.6 N.A. 100 N.A. 20 86.6 N.A. 86.6 93.3 86.6 80 N.A. N.A. 66.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 32.4 27.2 28
Protein Similarity: N.A. N.A. N.A. 50.5 44.3 47.2
P-Site Identity: N.A. N.A. N.A. 20 6.6 0
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 72 % A
% Cys: 0 0 0 0 72 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 72 0 8 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 8 8 0 8 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 29 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 15 0 0 0 36 15 0 50 8 0 15 8 0 0 % K
% Leu: 0 29 0 8 0 0 0 0 8 0 0 0 0 0 8 % L
% Met: 0 0 0 0 15 0 0 0 0 8 0 0 0 8 0 % M
% Asn: 0 8 8 0 0 0 58 65 8 0 0 36 0 0 8 % N
% Pro: 0 8 15 0 0 0 0 0 8 36 86 0 72 72 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % Q
% Arg: 8 0 0 8 0 43 8 0 0 0 0 0 8 8 0 % R
% Ser: 8 0 0 8 0 0 0 15 0 0 0 15 8 0 0 % S
% Thr: 79 8 0 0 8 8 0 0 22 0 0 8 0 0 0 % T
% Val: 0 36 0 0 0 15 15 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 79 0 0 0 8 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _