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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24D All Species: 28.48
Human Site: T875 Identified Species: 48.21
UniProt: O94855 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94855 NP_055637.2 1032 113010 T875 Y Q R Q L V M T M G V A D S Q
Chimpanzee Pan troglodytes XP_001145058 1094 118246 S937 Y V R Q L V T S M D V A E T N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535702 1171 127156 T1014 Y Q R Q L V M T M G V A D S Q
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 S929 F A M C Q V K S Q P L V H L M
Rat Rattus norvegicus NP_001102926 1095 118506 S938 Y V R Q L V S S M D V A E T N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513076 1029 112278 S872 Y Q R Q L V M S M G V A D T Q
Chicken Gallus gallus XP_420635 1038 113834 S881 Y H R Q L V M S M G V A D T Q
Frog Xenopus laevis NP_001087832 1126 123503 A969 Y I R Q L V S A M D V A D S H
Zebra Danio Brachydanio rerio XP_700597 1315 142554 A1160 Y L R Q L V S A M D V A E S H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 T1118 F V M Q A V A T M P I S I S V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 S993 W L M Q T V L S M D V V S T H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M291 1097 117779 S940 I N H V S S L S T P L A I P L
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 S792 Q P I N A T S S L F E R Y G L
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 S812 G I P D P E T S Q I V L P P P
Conservation
Percent
Protein Identity: 100 55.6 N.A. 81 N.A. 26.9 55.4 N.A. 76.1 75.3 54.3 49.9 N.A. N.A. 41.3 N.A. 47.6
Protein Similarity: 100 70.8 N.A. 83.5 N.A. 44.4 70.5 N.A. 85.3 84.9 69.3 61.6 N.A. N.A. 56.8 N.A. 63.1
P-Site Identity: 100 53.3 N.A. 100 N.A. 6.6 53.3 N.A. 86.6 80 66.6 60 N.A. N.A. 33.3 N.A. 26.6
P-Site Similarity: 100 73.3 N.A. 100 N.A. 26.6 73.3 N.A. 100 93.3 66.6 66.6 N.A. N.A. 53.3 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 32.4 27.2 28
Protein Similarity: N.A. N.A. N.A. 50.5 44.3 47.2
P-Site Identity: N.A. N.A. N.A. 6.6 0 6.6
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 15 0 8 15 0 0 0 65 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 36 0 0 36 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 8 0 22 0 0 % E
% Phe: 15 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 0 29 0 0 0 8 0 % G
% His: 0 8 8 0 0 0 0 0 0 0 0 0 8 0 22 % H
% Ile: 8 15 8 0 0 0 0 0 0 8 8 0 15 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 15 0 0 58 0 15 0 8 0 15 8 0 8 15 % L
% Met: 0 0 22 0 0 0 29 0 72 0 0 0 0 0 8 % M
% Asn: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 15 % N
% Pro: 0 8 8 0 8 0 0 0 0 22 0 0 8 15 8 % P
% Gln: 8 22 0 72 8 0 0 0 15 0 0 0 0 0 29 % Q
% Arg: 0 0 58 0 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 0 0 0 0 8 8 29 65 0 0 0 8 8 36 0 % S
% Thr: 0 0 0 0 8 8 15 22 8 0 0 0 0 36 0 % T
% Val: 0 22 0 8 0 79 0 0 0 0 72 15 0 0 8 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 58 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _