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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24D All Species: 8.18
Human Site: Y100 Identified Species: 13.85
UniProt: O94855 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94855 NP_055637.2 1032 113010 Y100 V A S S H A P Y Q P S A Q S S
Chimpanzee Pan troglodytes XP_001145058 1094 118246 P151 Q I S G A V A P A P P S S G L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535702 1171 127156 Y243 A A P S Y A P Y S P S A Q S S
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 P134 L P G A N P P P P L N W Q Y N
Rat Rattus norvegicus NP_001102926 1095 118506 S165 L G Y G P P T S L A S A S G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513076 1029 112278 Q101 P P F S H P S Q P P Y P N P A
Chicken Gallus gallus XP_420635 1038 113834 S110 T G P S Y P P S S L H S Q P A
Frog Xenopus laevis NP_001087832 1126 123503 S186 Y S S S Q G P S P I N L T Q G
Zebra Danio Brachydanio rerio XP_700597 1315 142554 A211 T A Q A P I S A A Y T P S A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 G248 S K V A L L H G Q N V S S T S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 G204 Y N M G G L P G G P Q P P P A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M291 1097 117779 F110 Q V S Q P G G F P P V G R P V
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 Q75 Q L H Q Q I D Q A T T S M N D
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 A89 Q Y G I P Q P A A P G F G G Y
Conservation
Percent
Protein Identity: 100 55.6 N.A. 81 N.A. 26.9 55.4 N.A. 76.1 75.3 54.3 49.9 N.A. N.A. 41.3 N.A. 47.6
Protein Similarity: 100 70.8 N.A. 83.5 N.A. 44.4 70.5 N.A. 85.3 84.9 69.3 61.6 N.A. N.A. 56.8 N.A. 63.1
P-Site Identity: 100 13.3 N.A. 73.3 N.A. 13.3 13.3 N.A. 20 20 20 6.6 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 20 N.A. 80 N.A. 46.6 26.6 N.A. 26.6 40 33.3 26.6 N.A. N.A. 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 32.4 27.2 28
Protein Similarity: N.A. N.A. N.A. 50.5 44.3 47.2
P-Site Identity: N.A. N.A. N.A. 13.3 0 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 22 0 22 8 15 8 15 29 8 0 22 0 8 22 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 8 0 0 0 8 0 0 0 % F
% Gly: 0 15 15 22 8 15 8 15 8 0 8 8 8 22 8 % G
% His: 0 0 8 0 15 0 8 0 0 0 8 0 0 0 0 % H
% Ile: 0 8 0 8 0 15 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 15 8 0 0 8 15 0 0 8 15 0 8 0 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 8 0 0 8 0 0 0 0 8 15 0 8 8 15 % N
% Pro: 8 15 15 0 29 29 50 15 29 50 8 22 8 29 8 % P
% Gln: 29 0 8 15 15 8 0 15 15 0 8 0 29 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % R
% Ser: 8 8 29 36 0 0 15 22 15 0 22 29 29 15 22 % S
% Thr: 15 0 0 0 0 0 8 0 0 8 15 0 8 8 0 % T
% Val: 8 8 8 0 0 8 0 0 0 0 15 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 15 8 8 0 15 0 0 15 0 8 8 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _