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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC24D
All Species:
25.15
Human Site:
Y351
Identified Species:
42.56
UniProt:
O94855
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94855
NP_055637.2
1032
113010
Y351
P
S
N
E
S
P
L
Y
L
V
N
H
G
E
S
Chimpanzee
Pan troglodytes
XP_001145058
1094
118246
Y413
P
P
E
E
A
S
P
Y
V
V
D
H
G
E
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535702
1171
127156
Y490
P
S
N
E
T
P
L
Y
L
V
N
H
G
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2P1
1090
118764
T388
E
L
F
R
C
T
L
T
S
V
P
Q
T
Q
A
Rat
Rattus norvegicus
NP_001102926
1095
118506
Y414
P
P
E
E
A
S
P
Y
V
V
D
H
G
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513076
1029
112278
Y352
P
A
N
E
T
P
L
Y
V
V
N
H
G
E
T
Chicken
Gallus gallus
XP_420635
1038
113834
Y357
P
Q
N
E
T
P
L
Y
V
V
N
H
G
E
A
Frog
Xenopus laevis
NP_001087832
1126
123503
C445
P
G
D
E
L
P
P
C
I
V
D
H
V
E
T
Zebra Danio
Brachydanio rerio
XP_700597
1315
142554
Y612
P
P
D
E
S
P
P
Y
L
V
D
H
G
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392952
1276
140829
P594
A
E
G
E
Y
E
P
P
I
V
D
M
G
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783728
1150
123558
P469
I
N
N
E
N
R
P
P
I
V
D
H
G
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M291
1097
117779
Q422
H
P
S
E
E
P
I
Q
V
V
D
F
G
E
S
Baker's Yeast
Sacchar. cerevisiae
P40482
926
103617
V312
T
Y
C
F
L
I
D
V
S
Q
S
S
I
K
S
Red Bread Mold
Neurospora crassa
Q7S4P3
950
103512
E326
V
D
R
W
Q
R
P
E
L
N
H
A
V
V
E
Conservation
Percent
Protein Identity:
100
55.6
N.A.
81
N.A.
26.9
55.4
N.A.
76.1
75.3
54.3
49.9
N.A.
N.A.
41.3
N.A.
47.6
Protein Similarity:
100
70.8
N.A.
83.5
N.A.
44.4
70.5
N.A.
85.3
84.9
69.3
61.6
N.A.
N.A.
56.8
N.A.
63.1
P-Site Identity:
100
53.3
N.A.
86.6
N.A.
13.3
53.3
N.A.
73.3
73.3
40
73.3
N.A.
N.A.
26.6
N.A.
33.3
P-Site Similarity:
100
73.3
N.A.
100
N.A.
26.6
73.3
N.A.
100
93.3
66.6
86.6
N.A.
N.A.
40
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.4
27.2
28
Protein Similarity:
N.A.
N.A.
N.A.
50.5
44.3
47.2
P-Site Identity:
N.A.
N.A.
N.A.
40
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
15
0
0
0
0
0
0
8
0
0
15
% A
% Cys:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
15
0
0
0
8
0
0
0
50
0
0
0
0
% D
% Glu:
8
8
15
79
8
8
0
8
0
0
0
0
0
72
8
% E
% Phe:
0
0
8
8
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
8
0
0
0
0
0
0
0
0
0
72
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
65
0
0
0
% H
% Ile:
8
0
0
0
0
8
8
0
22
0
0
0
8
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
8
0
0
15
0
36
0
29
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
36
0
8
0
0
0
0
8
29
0
0
0
15
% N
% Pro:
58
29
0
0
0
50
50
15
0
0
8
0
0
8
0
% P
% Gln:
0
8
0
0
8
0
0
8
0
8
0
8
0
8
0
% Q
% Arg:
0
0
8
8
0
15
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
8
0
15
15
0
0
15
0
8
8
0
0
43
% S
% Thr:
8
0
0
0
22
8
0
8
0
0
0
0
8
0
15
% T
% Val:
8
0
0
0
0
0
0
8
36
86
0
0
15
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _