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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFASC All Species: 17.88
Human Site: Y565 Identified Species: 43.7
UniProt: O94856 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94856 NP_001005389.2 1347 150027 Y565 L K D D E P L Y I G N R M K K
Chimpanzee Pan troglodytes XP_514129 1329 149138 Q549 M V N G E P L Q S A P P N P N
Rhesus Macaque Macaca mulatta XP_001097188 1345 149533 Y565 L K D D E P L Y I G N R M K K
Dog Lupus familis XP_848374 1343 149672 Y565 L K D D E P L Y I G N R M K K
Cat Felis silvestris
Mouse Mus musculus Q810U3 1240 137957 R492 S L E I K M I R K E D Q G I Y
Rat Rattus norvegicus P97685 1240 137986 R492 S L E I K M I R K E D Q G I Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507406 1330 147889 Y565 L K D N E P L Y I G N R L K K
Chicken Gallus gallus O42414 1369 152936 Y583 L K D D A P L Y I G N R M K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q90478 1197 132843 N449 S A D V E V L N R T K I V G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20241 1302 143599 N543 Q S A T F R C N E A H D D T L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.6 97.5 96.2 N.A. 88.2 88.4 N.A. 80.8 74.5 N.A. 31.3 N.A. 27.6 N.A. N.A. N.A.
Protein Similarity: 100 85.2 97.9 97.6 N.A. 89.9 90 N.A. 88.3 83.3 N.A. 47.4 N.A. 43.7 N.A. N.A. N.A.
P-Site Identity: 100 20 100 100 N.A. 0 0 N.A. 86.6 93.3 N.A. 20 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 33.3 33.3 N.A. 100 93.3 N.A. 26.6 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 10 0 0 0 0 20 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 60 40 0 0 0 0 0 0 20 10 10 0 0 % D
% Glu: 0 0 20 0 60 0 0 0 10 20 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 50 0 0 20 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 20 0 0 20 0 50 0 0 10 0 20 0 % I
% Lys: 0 50 0 0 20 0 0 0 20 0 10 0 0 50 50 % K
% Leu: 50 20 0 0 0 0 70 0 0 0 0 0 10 0 10 % L
% Met: 10 0 0 0 0 20 0 0 0 0 0 0 40 0 0 % M
% Asn: 0 0 10 10 0 0 0 20 0 0 50 0 10 0 10 % N
% Pro: 0 0 0 0 0 60 0 0 0 0 10 10 0 10 10 % P
% Gln: 10 0 0 0 0 0 0 10 0 0 0 20 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 20 10 0 0 50 0 0 0 % R
% Ser: 30 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 10 0 0 0 10 0 % T
% Val: 0 10 0 10 0 10 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 20 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _