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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMCC1
All Species:
17.27
Human Site:
Y487
Identified Species:
63.33
UniProt:
O94876
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94876
NP_001017395.2
653
72053
Y487
F
E
T
L
K
E
H
Y
Q
R
D
Y
S
L
I
Chimpanzee
Pan troglodytes
XP_001160985
709
77437
L544
M
E
D
L
K
T
Q
L
Q
R
D
Y
T
Y
M
Rhesus Macaque
Macaca mulatta
XP_001093910
653
72122
Y487
F
E
T
L
K
E
H
Y
Q
R
D
Y
S
L
I
Dog
Lupus familis
XP_541758
677
74708
Y511
F
E
T
L
K
E
H
Y
Q
R
D
Y
S
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZZ6
649
71624
Y483
F
E
T
L
K
E
H
Y
Q
R
D
Y
S
L
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506394
543
59742
K398
V
E
D
G
T
G
G
K
P
L
G
V
I
A
N
Chicken
Gallus gallus
XP_414456
649
71874
Y483
F
E
D
L
K
V
R
Y
Q
R
D
Y
S
L
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52
99.5
94.6
N.A.
95.4
N.A.
N.A.
73.9
89.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.7
99.6
94.9
N.A.
97.4
N.A.
N.A.
77
93.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
100
100
N.A.
100
N.A.
N.A.
6.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
100
100
N.A.
100
N.A.
N.A.
6.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
43
0
0
0
0
0
0
0
86
0
0
0
0
% D
% Glu:
0
100
0
0
0
58
0
0
0
0
0
0
0
0
0
% E
% Phe:
72
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
15
0
15
15
0
0
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
72
% I
% Lys:
0
0
0
0
86
0
0
15
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
86
0
0
0
15
0
15
0
0
0
72
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% N
% Pro:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
15
0
86
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
15
0
0
86
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
72
0
0
% S
% Thr:
0
0
58
0
15
15
0
0
0
0
0
0
15
0
0
% T
% Val:
15
0
0
0
0
15
0
0
0
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
72
0
0
0
86
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _