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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM63A
All Species:
21.52
Human Site:
S537
Identified Species:
47.33
UniProt:
O94886
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94886
NP_055513.1
807
92126
S537
R
W
L
F
D
K
T
S
S
E
A
S
I
R
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089796
853
97098
S585
R
W
L
F
D
K
T
S
S
K
A
S
I
R
L
Dog
Lupus familis
XP_547510
854
97136
S585
R
W
L
F
D
K
T
S
S
E
A
S
I
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91YT8
804
91841
S536
R
W
L
F
D
K
T
S
S
E
T
S
I
R
L
Rat
Rattus norvegicus
NP_001127968
804
91668
S536
R
W
L
F
D
K
T
S
S
D
T
S
I
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512688
801
91795
S539
R
W
L
F
D
R
A
S
A
E
P
S
V
R
L
Chicken
Gallus gallus
XP_419384
751
86211
M502
S
A
E
N
R
I
M
M
H
K
V
Y
I
F
L
Frog
Xenopus laevis
NP_001088752
803
91863
L539
R
W
L
F
D
R
A
L
D
Q
Q
G
S
V
R
Zebra Danio
Brachydanio rerio
XP_700116
801
91618
F537
R
W
L
F
D
K
K
F
L
D
E
A
T
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392828
767
85105
N517
E
W
T
V
N
V
T
N
D
T
G
R
W
D
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785977
734
83832
L484
F
H
W
T
R
T
K
L
N
H
T
I
M
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91.4
84.3
N.A.
89.7
87.9
N.A.
76
66.6
62.9
54.7
N.A.
N.A.
33.8
N.A.
35.6
Protein Similarity:
100
N.A.
92.8
89.1
N.A.
95
93.8
N.A.
86.4
79
78.1
71.2
N.A.
N.A.
54.4
N.A.
52.9
P-Site Identity:
100
N.A.
93.3
100
N.A.
93.3
86.6
N.A.
66.6
13.3
33.3
40
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
86.6
20
46.6
53.3
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
19
0
10
0
28
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
73
0
0
0
19
19
0
0
0
10
0
% D
% Glu:
10
0
10
0
0
0
0
0
0
37
10
0
0
0
0
% E
% Phe:
10
0
0
73
0
0
0
10
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
10
55
10
0
% I
% Lys:
0
0
0
0
0
55
19
0
0
19
0
0
0
0
10
% K
% Leu:
0
0
73
0
0
0
0
19
10
0
0
0
0
0
64
% L
% Met:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
10
10
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% Q
% Arg:
73
0
0
0
19
19
0
0
0
0
0
10
0
64
19
% R
% Ser:
10
0
0
0
0
0
0
55
46
0
0
55
10
0
0
% S
% Thr:
0
0
10
10
0
10
55
0
0
10
28
0
10
0
0
% T
% Val:
0
0
0
10
0
10
0
0
0
0
10
0
10
10
0
% V
% Trp:
0
82
10
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _