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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM63A
All Species:
20
Human Site:
Y286
Identified Species:
44
UniProt:
O94886
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94886
NP_055513.1
807
92126
Y286
T
E
K
S
L
T
Y
Y
T
N
L
Q
V
K
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089796
853
97098
Y339
T
E
K
S
L
T
Y
Y
T
N
L
Q
V
K
T
Dog
Lupus familis
XP_547510
854
97136
Y334
A
E
K
S
L
T
Y
Y
T
N
L
Q
A
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91YT8
804
91841
Y285
T
E
K
S
L
T
Y
Y
T
N
L
Q
A
K
T
Rat
Rattus norvegicus
NP_001127968
804
91668
Y285
T
E
K
S
L
T
Y
Y
T
N
L
Q
V
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512688
801
91795
F288
A
E
K
S
L
T
Y
F
T
N
L
Q
N
K
T
Chicken
Gallus gallus
XP_419384
751
86211
D264
L
E
V
Q
L
C
Y
D
V
A
R
L
I
H
L
Frog
Xenopus laevis
NP_001088752
803
91863
F288
A
E
K
N
L
A
Y
F
T
N
L
L
N
K
T
Zebra Danio
Brachydanio rerio
XP_700116
801
91618
Y286
A
E
R
S
K
K
F
Y
T
D
L
M
S
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392828
767
85105
E279
R
L
S
A
L
N
V
E
R
D
C
A
E
Q
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785977
734
83832
A246
I
K
Q
H
F
Q
E
A
Y
P
D
V
V
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91.4
84.3
N.A.
89.7
87.9
N.A.
76
66.6
62.9
54.7
N.A.
N.A.
33.8
N.A.
35.6
Protein Similarity:
100
N.A.
92.8
89.1
N.A.
95
93.8
N.A.
86.4
79
78.1
71.2
N.A.
N.A.
54.4
N.A.
52.9
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
100
N.A.
80
20
60
33.3
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
N.A.
100
86.6
N.A.
93.3
100
N.A.
86.6
26.6
73.3
60
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
0
0
10
0
10
0
10
0
10
0
10
19
0
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
19
10
0
0
0
0
% D
% Glu:
0
82
0
0
0
0
10
10
0
0
0
0
10
0
10
% E
% Phe:
0
0
0
0
10
0
10
19
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
64
0
10
10
0
0
0
0
0
0
0
64
0
% K
% Leu:
10
10
0
0
82
0
0
0
0
0
73
19
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
0
64
0
0
19
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
10
10
0
10
0
0
0
0
0
55
0
10
0
% Q
% Arg:
10
0
10
0
0
0
0
0
10
0
10
0
0
10
0
% R
% Ser:
0
0
10
64
0
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
37
0
0
0
0
55
0
0
73
0
0
0
0
0
73
% T
% Val:
0
0
10
0
0
0
10
0
10
0
0
10
37
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
73
55
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _