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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM63A
All Species:
19.7
Human Site:
Y323
Identified Species:
43.33
UniProt:
O94886
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94886
NP_055513.1
807
92126
Y323
E
W
E
D
A
I
S
Y
Y
T
R
M
K
D
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089796
853
97098
L366
Q
F
C
C
C
E
V
L
G
C
E
W
E
D
A
Dog
Lupus familis
XP_547510
854
97136
Y371
E
W
E
D
A
I
S
Y
Y
T
R
L
K
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91YT8
804
91841
Y322
E
R
E
D
A
I
S
Y
Y
T
R
M
N
D
S
Rat
Rattus norvegicus
NP_001127968
804
91668
Y322
E
R
E
D
A
I
S
Y
Y
T
R
M
N
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512688
801
91795
Y325
E
R
E
D
A
V
S
Y
Y
S
R
M
K
D
D
Chicken
Gallus gallus
XP_419384
751
86211
K291
Y
Y
K
R
L
Y
E
K
H
G
K
R
A
K
I
Frog
Xenopus laevis
NP_001088752
803
91863
H325
E
K
E
D
A
I
E
H
Y
S
K
V
R
D
K
Zebra Danio
Brachydanio rerio
XP_700116
801
91618
Y323
E
Q
E
E
A
V
N
Y
Y
T
K
L
E
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392828
767
85105
P306
P
L
Q
M
Y
P
Y
P
C
G
Q
V
I
G
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785977
734
83832
D273
R
L
D
T
Q
R
R
D
A
H
L
N
R
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91.4
84.3
N.A.
89.7
87.9
N.A.
76
66.6
62.9
54.7
N.A.
N.A.
33.8
N.A.
35.6
Protein Similarity:
100
N.A.
92.8
89.1
N.A.
95
93.8
N.A.
86.4
79
78.1
71.2
N.A.
N.A.
54.4
N.A.
52.9
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
80
80
N.A.
73.3
0
46.6
40
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
N.A.
26.6
100
N.A.
80
80
N.A.
86.6
26.6
86.6
86.6
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
64
0
0
0
10
0
0
0
10
10
10
% A
% Cys:
0
0
10
10
10
0
0
0
10
10
0
0
0
0
10
% C
% Asp:
0
0
10
55
0
0
0
10
0
0
0
0
0
64
10
% D
% Glu:
64
0
64
10
0
10
19
0
0
0
10
0
19
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
19
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
10
10
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
46
0
0
0
0
0
0
10
0
10
% I
% Lys:
0
10
10
0
0
0
0
10
0
0
28
0
28
10
19
% K
% Leu:
0
19
0
0
10
0
0
10
0
0
10
19
0
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
37
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
10
19
0
0
% N
% Pro:
10
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% P
% Gln:
10
10
10
0
10
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
10
28
0
10
0
10
10
0
0
0
46
10
19
0
19
% R
% Ser:
0
0
0
0
0
0
46
0
0
19
0
0
0
0
19
% S
% Thr:
0
0
0
10
0
0
0
0
0
46
0
0
0
0
0
% T
% Val:
0
0
0
0
0
19
10
0
0
0
0
19
0
0
0
% V
% Trp:
0
19
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
10
10
0
0
10
10
10
55
64
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _