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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL18
All Species:
20
Human Site:
S171
Identified Species:
40
UniProt:
O94889
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94889
NP_079286.2
574
63638
S171
H
Q
H
F
V
E
V
S
M
S
E
E
F
L
A
Chimpanzee
Pan troglodytes
XP_001144888
634
70234
S231
H
Q
H
F
V
E
V
S
M
S
E
E
F
L
A
Rhesus Macaque
Macaca mulatta
XP_001100798
545
60330
E153
E
F
L
A
L
P
L
E
D
V
L
E
L
V
S
Dog
Lupus familis
XP_541899
694
76472
S291
H
Q
H
F
V
D
V
S
M
S
E
E
F
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK5
604
67393
M196
Q
H
N
F
Q
E
V
M
E
S
E
E
F
M
L
Rat
Rattus norvegicus
Q8K430
640
69714
A223
L
Q
H
F
V
D
V
A
K
T
E
E
F
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026131
584
64965
S176
H
Q
H
F
V
E
V
S
M
S
E
E
F
L
A
Frog
Xenopus laevis
Q6NRH0
564
63190
V162
Q
K
H
F
P
E
V
V
Q
H
E
E
F
M
L
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
V162
Q
K
H
F
A
E
V
V
Q
Q
E
E
F
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
M205
Q
H
N
F
Q
E
V
M
E
S
E
E
F
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_499785
589
66577
S185
Q
K
H
F
M
A
V
S
K
D
E
D
F
K
R
Sea Urchin
Strong. purpuratus
XP_783729
575
63988
S173
H
K
Q
F
V
D
V
S
S
S
D
E
F
M
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
92.6
80.1
N.A.
40.4
39.8
N.A.
N.A.
90.4
40.5
40.9
N.A.
39.4
N.A.
43.1
58.9
Protein Similarity:
100
90.2
93.5
81.1
N.A.
58.9
54.8
N.A.
N.A.
94.6
55.7
56.4
N.A.
56.8
N.A.
61.1
75.6
P-Site Identity:
100
100
6.6
93.3
N.A.
46.6
53.3
N.A.
N.A.
100
46.6
46.6
N.A.
53.3
N.A.
40
53.3
P-Site Similarity:
100
100
33.3
100
N.A.
60
80
N.A.
N.A.
100
60
60
N.A.
60
N.A.
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
9
0
9
0
0
0
0
0
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
25
0
0
9
9
9
9
0
0
0
% D
% Glu:
9
0
0
0
0
59
0
9
17
0
84
92
0
0
0
% E
% Phe:
0
9
0
92
0
0
0
0
0
0
0
0
92
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
42
17
67
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
34
0
0
0
0
0
0
17
0
0
0
0
9
0
% K
% Leu:
9
0
9
0
9
0
9
0
0
0
9
0
9
42
42
% L
% Met:
0
0
0
0
9
0
0
17
34
0
0
0
0
42
9
% M
% Asn:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
42
42
9
0
17
0
0
0
17
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
0
0
0
0
0
50
9
59
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
50
0
92
17
0
9
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _