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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL18
All Species:
10.91
Human Site:
S18
Identified Species:
21.82
UniProt:
O94889
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94889
NP_079286.2
574
63638
S18
D
L
V
H
F
S
V
S
E
L
P
S
R
G
Y
Chimpanzee
Pan troglodytes
XP_001144888
634
70234
S78
D
L
V
H
F
S
V
S
E
L
P
S
R
G
Y
Rhesus Macaque
Macaca mulatta
XP_001100798
545
60330
A10
W
D
A
L
N
T
V
A
M
G
S
G
I
G
D
Dog
Lupus familis
XP_541899
694
76472
S138
D
L
V
H
F
S
V
S
E
L
P
S
R
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK5
604
67393
D43
A
R
M
P
Y
I
S
D
K
H
P
R
Q
T
L
Rat
Rattus norvegicus
Q8K430
640
69714
Q56
A
P
M
E
G
A
M
Q
L
L
S
R
E
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026131
584
64965
G23
D
L
V
H
F
S
V
G
D
L
P
S
R
G
Y
Frog
Xenopus laevis
Q6NRH0
564
63190
S10
P
K
D
I
M
T
N
S
H
A
K
S
I
L
N
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
S10
P
K
D
I
M
T
N
S
H
A
K
S
I
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
E52
A
R
L
S
H
T
S
E
K
H
P
K
V
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_499785
589
66577
D31
F
I
K
V
D
I
L
D
E
M
Y
K
K
S
Y
Sea Urchin
Strong. purpuratus
XP_783729
575
63988
N20
D
S
V
A
F
C
M
N
D
L
P
A
D
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
92.6
80.1
N.A.
40.4
39.8
N.A.
N.A.
90.4
40.5
40.9
N.A.
39.4
N.A.
43.1
58.9
Protein Similarity:
100
90.2
93.5
81.1
N.A.
58.9
54.8
N.A.
N.A.
94.6
55.7
56.4
N.A.
56.8
N.A.
61.1
75.6
P-Site Identity:
100
100
13.3
100
N.A.
6.6
13.3
N.A.
N.A.
86.6
13.3
13.3
N.A.
6.6
N.A.
13.3
46.6
P-Site Similarity:
100
100
26.6
100
N.A.
33.3
40
N.A.
N.A.
93.3
20
20
N.A.
26.6
N.A.
40
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
9
9
0
9
0
9
0
17
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
9
17
0
9
0
0
17
17
0
0
0
9
0
9
% D
% Glu:
0
0
0
9
0
0
0
9
34
0
0
0
9
0
0
% E
% Phe:
9
0
0
0
42
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
9
0
9
0
9
0
59
0
% G
% His:
0
0
0
34
9
0
0
0
17
17
0
0
0
0
9
% H
% Ile:
0
9
0
17
0
17
0
0
0
0
0
0
25
0
0
% I
% Lys:
0
17
9
0
0
0
0
0
17
0
17
17
9
0
0
% K
% Leu:
0
34
9
9
0
0
9
0
9
50
0
0
0
17
17
% L
% Met:
0
0
17
0
17
0
17
0
9
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
17
9
0
0
0
0
0
0
17
% N
% Pro:
17
9
0
9
0
0
0
0
0
0
59
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% Q
% Arg:
0
17
0
0
0
0
0
0
0
0
0
17
34
0
0
% R
% Ser:
0
9
0
9
0
34
17
42
0
0
17
50
0
9
0
% S
% Thr:
0
0
0
0
0
34
0
0
0
0
0
0
0
17
0
% T
% Val:
0
0
42
9
0
0
42
0
0
0
0
0
9
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _