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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL18
All Species:
18.18
Human Site:
S351
Identified Species:
36.36
UniProt:
O94889
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94889
NP_079286.2
574
63638
S351
Y
D
G
Q
L
R
L
S
T
V
E
A
Y
N
P
Chimpanzee
Pan troglodytes
XP_001144888
634
70234
S411
Y
D
G
Q
L
R
L
S
T
V
E
A
Y
N
P
Rhesus Macaque
Macaca mulatta
XP_001100798
545
60330
S322
Y
D
G
Q
L
R
L
S
T
V
E
A
Y
N
P
Dog
Lupus familis
XP_541899
694
76472
S471
Y
D
G
Q
L
R
L
S
T
V
E
V
Y
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK5
604
67393
S376
D
G
S
S
Y
L
N
S
V
E
R
Y
D
P
K
Rat
Rattus norvegicus
Q8K430
640
69714
A402
Y
D
G
T
S
D
L
A
T
V
E
S
Y
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026131
584
64965
S361
Y
D
G
Q
L
R
L
S
T
V
E
V
Y
N
P
Frog
Xenopus laevis
Q6NRH0
564
63190
E343
R
S
R
L
S
S
V
E
C
L
D
Y
T
S
E
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
E343
R
S
R
L
S
S
V
E
C
L
D
Y
T
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
S385
D
G
Q
S
Y
L
N
S
I
E
R
Y
D
P
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_499785
589
66577
D364
F
N
G
Q
D
R
L
D
L
V
E
K
F
D
Y
Sea Urchin
Strong. purpuratus
XP_783729
575
63988
N353
Y
D
G
Q
S
R
L
N
T
V
E
V
F
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
92.6
80.1
N.A.
40.4
39.8
N.A.
N.A.
90.4
40.5
40.9
N.A.
39.4
N.A.
43.1
58.9
Protein Similarity:
100
90.2
93.5
81.1
N.A.
58.9
54.8
N.A.
N.A.
94.6
55.7
56.4
N.A.
56.8
N.A.
61.1
75.6
P-Site Identity:
100
100
100
93.3
N.A.
6.6
60
N.A.
N.A.
93.3
0
0
N.A.
6.6
N.A.
40
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
6.6
80
N.A.
N.A.
93.3
26.6
20
N.A.
6.6
N.A.
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
0
25
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% C
% Asp:
17
59
0
0
9
9
0
9
0
0
17
0
17
25
9
% D
% Glu:
0
0
0
0
0
0
0
17
0
17
67
0
0
0
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% F
% Gly:
0
17
67
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% K
% Leu:
0
0
0
17
42
17
67
0
9
17
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
17
9
0
0
0
0
0
42
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
59
% P
% Gln:
0
0
9
59
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
17
0
17
0
0
59
0
0
0
0
17
0
0
0
0
% R
% Ser:
0
17
9
17
34
17
0
59
0
0
0
9
0
9
0
% S
% Thr:
0
0
0
9
0
0
0
0
59
0
0
0
17
0
0
% T
% Val:
0
0
0
0
0
0
17
0
9
67
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
59
0
0
0
17
0
0
0
0
0
0
34
50
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _