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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL18
All Species:
22.42
Human Site:
S368
Identified Species:
44.85
UniProt:
O94889
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94889
NP_079286.2
574
63638
S368
D
T
W
T
R
V
G
S
M
N
S
K
R
S
A
Chimpanzee
Pan troglodytes
XP_001144888
634
70234
S428
D
T
W
T
R
V
G
S
M
N
S
K
R
S
A
Rhesus Macaque
Macaca mulatta
XP_001100798
545
60330
S339
D
T
W
T
R
V
G
S
M
N
S
K
R
S
A
Dog
Lupus familis
XP_541899
694
76472
S488
D
T
W
T
R
V
R
S
M
N
S
K
R
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK5
604
67393
P393
Q
W
S
S
D
V
A
P
T
S
T
C
R
T
S
Rat
Rattus norvegicus
Q8K430
640
69714
S419
N
T
W
Q
P
E
V
S
M
G
T
R
R
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026131
584
64965
S378
D
S
W
S
K
V
E
S
M
N
S
K
R
S
A
Frog
Xenopus laevis
Q6NRH0
564
63190
P360
G
V
W
Y
S
V
A
P
M
N
V
R
R
G
L
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
T360
G
V
W
Y
S
V
A
T
M
N
V
R
R
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
P402
Q
W
S
C
D
V
A
P
T
T
S
C
R
T
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_499785
589
66577
P381
L
K
W
T
T
L
S
P
L
T
R
K
R
S
A
Sea Urchin
Strong. purpuratus
XP_783729
575
63988
P370
Y
E
W
W
D
V
A
P
M
N
H
R
R
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
92.6
80.1
N.A.
40.4
39.8
N.A.
N.A.
90.4
40.5
40.9
N.A.
39.4
N.A.
43.1
58.9
Protein Similarity:
100
90.2
93.5
81.1
N.A.
58.9
54.8
N.A.
N.A.
94.6
55.7
56.4
N.A.
56.8
N.A.
61.1
75.6
P-Site Identity:
100
100
100
93.3
N.A.
13.3
40
N.A.
N.A.
73.3
33.3
33.3
N.A.
20
N.A.
40
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
46.6
60
N.A.
N.A.
93.3
40
46.6
N.A.
33.3
N.A.
53.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
42
0
0
0
0
0
0
0
59
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
17
0
0
9
% C
% Asp:
42
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
9
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
0
25
0
0
9
0
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
9
0
0
0
0
0
0
50
0
0
0
% K
% Leu:
9
0
0
0
0
9
0
0
9
0
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
42
0
0
0
0
0
0
0
% P
% Gln:
17
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
34
0
9
0
0
0
9
34
100
0
0
% R
% Ser:
0
9
17
17
17
0
9
50
0
9
50
0
0
67
17
% S
% Thr:
0
42
0
42
9
0
0
9
17
17
17
0
0
17
0
% T
% Val:
0
17
0
0
0
84
9
0
0
0
17
0
0
0
0
% V
% Trp:
0
17
84
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _