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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL18 All Species: 36.36
Human Site: S536 Identified Species: 72.73
UniProt: O94889 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94889 NP_079286.2 574 63638 S536 V G G Y D G Q S N L S S V E M
Chimpanzee Pan troglodytes XP_001144888 634 70234 S596 V G G Y D G Q S N L S S V E M
Rhesus Macaque Macaca mulatta XP_001100798 545 60330 S507 V G G Y D G Q S N L S S V E M
Dog Lupus familis XP_541899 694 76472 S656 V G G Y D G Q S N L S S V E M
Cat Felis silvestris
Mouse Mus musculus Q8VCK5 604 67393 T561 V G G F D G T T Y L K T I E V
Rat Rattus norvegicus Q8K430 640 69714 S587 V G G N D G S S S L N S I E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026131 584 64965 S546 V G G Y D G Q S N L S S V E M
Frog Xenopus laevis Q6NRH0 564 63190 S528 I A G Y D G N S L L N S V E C
Zebra Danio Brachydanio rerio Q5U374 564 62914 S528 I A G Y D G N S L L S S I E C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 A570 V G G F D G S A Y L K T I E V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_499785 589 66577 N549 V A G F D G E N N L C S M E Q
Sea Urchin Strong. purpuratus XP_783729 575 63988 T538 V G G Y D G L T N L N T V E M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.2 92.6 80.1 N.A. 40.4 39.8 N.A. N.A. 90.4 40.5 40.9 N.A. 39.4 N.A. 43.1 58.9
Protein Similarity: 100 90.2 93.5 81.1 N.A. 58.9 54.8 N.A. N.A. 94.6 55.7 56.4 N.A. 56.8 N.A. 61.1 75.6
P-Site Identity: 100 100 100 100 N.A. 46.6 60 N.A. N.A. 100 60 60 N.A. 46.6 N.A. 53.3 73.3
P-Site Similarity: 100 100 100 100 N.A. 80 80 N.A. N.A. 100 73.3 73.3 N.A. 80 N.A. 80 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 0 0 0 0 0 9 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 17 % C
% Asp: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 9 0 0 0 0 0 0 100 0 % E
% Phe: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 75 100 0 0 100 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 0 0 0 0 0 0 0 0 0 0 0 34 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 9 % K
% Leu: 0 0 0 0 0 0 9 0 17 100 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 50 % M
% Asn: 0 0 0 9 0 0 17 9 59 0 25 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 42 0 0 0 0 0 0 0 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 17 67 9 0 50 75 0 0 0 % S
% Thr: 0 0 0 0 0 0 9 17 0 0 0 25 0 0 0 % T
% Val: 84 0 0 0 0 0 0 0 0 0 0 0 59 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 67 0 0 0 0 17 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _