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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL18
All Species:
34.85
Human Site:
T411
Identified Species:
69.7
UniProt:
O94889
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94889
NP_079286.2
574
63638
T411
S
P
E
T
D
K
W
T
V
V
T
S
M
S
S
Chimpanzee
Pan troglodytes
XP_001144888
634
70234
T471
S
P
E
T
D
K
W
T
V
V
T
S
M
S
S
Rhesus Macaque
Macaca mulatta
XP_001100798
545
60330
T382
S
P
E
T
D
K
W
T
V
V
T
P
M
S
S
Dog
Lupus familis
XP_541899
694
76472
T531
S
P
E
T
D
K
W
T
V
V
T
P
M
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK5
604
67393
T436
D
P
K
E
N
K
W
T
R
V
A
S
M
S
T
Rat
Rattus norvegicus
Q8K430
640
69714
T462
D
P
L
T
G
T
W
T
S
I
A
A
M
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026131
584
64965
T421
S
P
E
T
N
K
W
T
V
V
T
P
M
S
S
Frog
Xenopus laevis
Q6NRH0
564
63190
S403
D
P
N
I
D
Q
W
S
M
L
G
D
M
Q
T
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
S403
D
P
N
I
D
Q
W
S
M
L
G
D
M
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
S445
D
P
K
E
N
K
W
S
K
V
A
P
M
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_499785
589
66577
E424
D
I
N
R
N
V
W
E
A
G
P
P
M
E
N
Sea Urchin
Strong. purpuratus
XP_783729
575
63988
Y413
D
P
E
T
N
K
W
Y
V
V
A
D
M
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
92.6
80.1
N.A.
40.4
39.8
N.A.
N.A.
90.4
40.5
40.9
N.A.
39.4
N.A.
43.1
58.9
Protein Similarity:
100
90.2
93.5
81.1
N.A.
58.9
54.8
N.A.
N.A.
94.6
55.7
56.4
N.A.
56.8
N.A.
61.1
75.6
P-Site Identity:
100
100
93.3
93.3
N.A.
53.3
40
N.A.
N.A.
86.6
26.6
26.6
N.A.
33.3
N.A.
13.3
53.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
73.3
60
N.A.
N.A.
93.3
60
60
N.A.
66.6
N.A.
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
34
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
59
0
0
0
50
0
0
0
0
0
0
25
0
0
0
% D
% Glu:
0
0
50
17
0
0
0
9
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
9
17
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
17
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
17
0
0
67
0
0
9
0
0
0
0
0
9
% K
% Leu:
0
0
9
0
0
0
0
0
0
17
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
17
0
0
0
100
0
0
% M
% Asn:
0
0
25
0
42
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
92
0
0
0
0
0
0
0
0
9
42
0
0
0
% P
% Gln:
0
0
0
0
0
17
0
0
0
0
0
0
0
17
0
% Q
% Arg:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
42
0
0
0
0
0
0
25
9
0
0
25
0
59
42
% S
% Thr:
0
0
0
59
0
9
0
59
0
0
42
0
0
17
42
% T
% Val:
0
0
0
0
0
9
0
0
50
67
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _