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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL18 All Species: 29.39
Human Site: T512 Identified Species: 58.79
UniProt: O94889 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94889 NP_079286.2 574 63638 T512 C L I V P M H T R R S R V S L
Chimpanzee Pan troglodytes XP_001144888 634 70234 T572 C L I V P M H T R R S R V S L
Rhesus Macaque Macaca mulatta XP_001100798 545 60330 T483 C L I V P M H T R R S R V S L
Dog Lupus familis XP_541899 694 76472 T632 C L I V P M L T R R S R V S L
Cat Felis silvestris
Mouse Mus musculus Q8VCK5 604 67393 S537 S P V V A M T S R R S G V G L
Rat Rattus norvegicus Q8K430 640 69714 I563 E S V A P M N I R R S T H D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026131 584 64965 T522 Y L I V P M N T R R S R V S L
Frog Xenopus laevis Q6NRH0 564 63190 T504 T T M T S M T T P R C Y V G A
Zebra Danio Brachydanio rerio Q5U374 564 62914 T504 T T V A N M T T P R C Y V G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 S546 S P I V A M T S R R S G V G L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_499785 589 66577 M525 S P V S P M N M R R S R V S L
Sea Urchin Strong. purpuratus XP_783729 575 63988 S514 T Y A A P M N S R R S R V A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.2 92.6 80.1 N.A. 40.4 39.8 N.A. N.A. 90.4 40.5 40.9 N.A. 39.4 N.A. 43.1 58.9
Protein Similarity: 100 90.2 93.5 81.1 N.A. 58.9 54.8 N.A. N.A. 94.6 55.7 56.4 N.A. 56.8 N.A. 61.1 75.6
P-Site Identity: 100 100 100 93.3 N.A. 46.6 40 N.A. N.A. 86.6 26.6 26.6 N.A. 53.3 N.A. 60 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 60 53.3 N.A. N.A. 93.3 33.3 33.3 N.A. 60 N.A. 73.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 25 17 0 0 0 0 0 0 0 0 9 17 % A
% Cys: 34 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 17 0 34 0 % G
% His: 0 0 0 0 0 0 25 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 50 0 0 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 42 0 0 0 0 9 0 0 0 0 0 0 0 84 % L
% Met: 0 0 9 0 0 100 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 34 0 0 0 0 0 0 0 0 % N
% Pro: 0 25 0 0 67 0 0 0 17 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 84 100 0 59 0 0 0 % R
% Ser: 25 9 0 9 9 0 0 25 0 0 84 0 0 50 0 % S
% Thr: 25 17 0 9 0 0 34 59 0 0 0 9 0 0 0 % T
% Val: 0 0 34 59 0 0 0 0 0 0 0 0 92 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 9 0 0 0 0 0 0 0 0 0 17 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _