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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL18
All Species:
34.24
Human Site:
Y433
Identified Species:
68.48
UniProt:
O94889
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94889
NP_079286.2
574
63638
Y433
T
V
F
E
G
R
I
Y
V
S
G
G
H
D
G
Chimpanzee
Pan troglodytes
XP_001144888
634
70234
Y493
T
V
F
E
G
R
I
Y
V
S
G
G
H
D
G
Rhesus Macaque
Macaca mulatta
XP_001100798
545
60330
Y404
T
V
F
E
G
R
I
Y
V
S
G
G
H
D
G
Dog
Lupus familis
XP_541899
694
76472
Y553
T
V
F
E
G
R
I
Y
V
S
G
G
H
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK5
604
67393
Y458
A
V
L
G
G
F
L
Y
A
V
G
G
S
D
G
Rat
Rattus norvegicus
Q8K430
640
69714
Y484
A
T
L
D
G
N
L
Y
A
V
G
G
Y
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026131
584
64965
Y443
T
V
F
E
G
R
I
Y
V
S
G
G
H
D
G
Frog
Xenopus laevis
Q6NRH0
564
63190
Y425
V
V
A
N
G
V
I
Y
C
L
G
G
Y
D
G
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
Y425
V
V
A
S
G
L
I
Y
C
L
G
G
Y
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
Y467
A
V
L
G
G
F
L
Y
A
I
G
G
S
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_499785
589
66577
Y446
T
V
I
D
K
H
I
Y
I
C
G
G
H
D
G
Sea Urchin
Strong. purpuratus
XP_783729
575
63988
F435
A
V
L
S
G
E
I
F
A
A
G
G
H
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
92.6
80.1
N.A.
40.4
39.8
N.A.
N.A.
90.4
40.5
40.9
N.A.
39.4
N.A.
43.1
58.9
Protein Similarity:
100
90.2
93.5
81.1
N.A.
58.9
54.8
N.A.
N.A.
94.6
55.7
56.4
N.A.
56.8
N.A.
61.1
75.6
P-Site Identity:
100
100
100
100
N.A.
46.6
33.3
N.A.
N.A.
100
53.3
53.3
N.A.
46.6
N.A.
60
53.3
P-Site Similarity:
100
100
100
100
N.A.
53.3
53.3
N.A.
N.A.
100
60
60
N.A.
53.3
N.A.
73.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
17
0
0
0
0
0
34
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
17
9
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
0
0
0
0
0
0
0
0
100
0
% D
% Glu:
0
0
0
42
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
42
0
0
17
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
92
0
0
0
0
0
100
100
0
0
92
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
59
0
0
% H
% Ile:
0
0
9
0
0
0
75
0
9
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
34
0
0
9
25
0
0
17
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
17
0
0
0
0
0
42
0
0
17
0
9
% S
% Thr:
50
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
17
92
0
0
0
9
0
0
42
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _