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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRIG2
All Species:
7.27
Human Site:
Y946
Identified Species:
17.78
UniProt:
O94898
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94898
NP_055628.1
1065
118965
Y946
V
Q
M
P
K
E
T
Y
L
V
H
P
P
Q
D
Chimpanzee
Pan troglodytes
XP_509180
1061
116817
C948
F
E
T
Y
H
T
G
C
S
P
D
P
R
T
V
Rhesus Macaque
Macaca mulatta
XP_001116574
948
104161
R836
I
I
Y
H
T
R
R
R
N
E
D
C
S
I
T
Dog
Lupus familis
XP_540333
1245
137678
Y1126
V
Q
M
P
K
E
T
Y
L
A
H
P
P
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q52KR2
1054
117844
P941
S
S
L
M
V
Q
M
P
K
E
T
F
L
S
H
Rat
Rattus norvegicus
NP_001101180
1054
117764
P941
S
S
L
M
V
Q
M
P
K
E
T
F
L
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506660
1107
123178
Y985
V
Q
M
P
K
E
T
Y
A
T
R
A
S
Q
E
Chicken
Gallus gallus
XP_416055
1099
121337
C927
F
E
A
C
S
P
S
C
S
P
D
Q
R
T
A
Frog
Xenopus laevis
NP_001103840
1107
123437
M941
I
F
H
A
G
Y
S
M
D
R
R
T
P
N
A
Zebra Danio
Brachydanio rerio
XP_001920857
995
110904
P883
S
H
Q
Q
L
M
P
P
A
N
G
Y
L
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.4
56.7
79.4
N.A.
89.6
89.6
N.A.
78.4
57.7
51.9
87.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.2
70
82.1
N.A.
93.8
93.3
N.A.
85.3
70.7
67.4
89.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
93.3
N.A.
0
0
N.A.
60
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
6.6
93.3
N.A.
13.3
13.3
N.A.
66.6
13.3
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
0
20
10
0
10
0
0
20
% A
% Cys:
0
0
0
10
0
0
0
20
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
30
0
0
0
20
% D
% Glu:
0
20
0
0
0
30
0
0
0
30
0
0
0
0
10
% E
% Phe:
20
10
0
0
0
0
0
0
0
0
0
20
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
0
0
10
0
0
0
0
% G
% His:
0
10
10
10
10
0
0
0
0
0
20
0
0
10
20
% H
% Ile:
20
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
30
0
0
0
20
0
0
0
0
0
10
% K
% Leu:
0
0
20
0
10
0
0
0
20
0
0
0
30
0
0
% L
% Met:
0
0
30
20
0
10
20
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% N
% Pro:
0
0
0
30
0
10
10
30
0
20
0
30
30
0
0
% P
% Gln:
0
30
10
10
0
20
0
0
0
0
0
10
0
30
0
% Q
% Arg:
0
0
0
0
0
10
10
10
0
10
20
0
20
0
0
% R
% Ser:
30
20
0
0
10
0
20
0
20
0
0
0
20
20
0
% S
% Thr:
0
0
10
0
10
10
30
0
0
10
20
10
0
20
10
% T
% Val:
30
0
0
0
20
0
0
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
10
0
30
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _