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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOX
All Species:
19.39
Human Site:
S266
Identified Species:
47.41
UniProt:
O94900
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94900
NP_055544.1
526
57513
S266
N
E
P
Q
K
P
V
S
A
Y
A
L
F
F
R
Chimpanzee
Pan troglodytes
XP_001165206
577
63461
S260
N
E
P
Q
K
P
V
S
A
Y
A
L
F
F
R
Rhesus Macaque
Macaca mulatta
XP_001088869
526
57464
S266
N
E
P
Q
K
P
V
S
A
Y
A
L
F
F
R
Dog
Lupus familis
XP_544093
508
55623
S248
N
E
P
Q
K
P
V
S
A
Y
A
L
F
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q66JW3
526
57184
S266
N
E
P
Q
K
P
V
S
A
Y
A
L
F
F
R
Rat
Rattus norvegicus
Q76IQ7
473
49858
D217
A
Y
A
L
F
F
R
D
T
Q
A
A
I
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513558
310
33659
S54
S
Q
D
Y
V
P
A
S
Q
S
Y
P
G
P
S
Chicken
Gallus gallus
NP_001026196
239
25856
Frog
Xenopus laevis
Q6IRR0
594
63660
A287
K
E
Y
L
K
A
L
A
L
Y
K
A
N
Q
L
Zebra Danio
Brachydanio rerio
XP_001919539
539
58316
A240
S
P
P
E
S
K
S
A
T
P
S
P
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.7
99.8
91.8
N.A.
94.3
41.6
N.A.
56.8
42.7
37.8
62.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
58.5
99.8
94.3
N.A.
96.1
54.5
N.A.
57.5
43.7
53.8
73.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
13.3
0
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
26.6
0
33.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
10
10
20
50
0
60
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
60
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
10
0
0
0
0
0
0
50
50
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
10
0
0
0
60
10
0
0
0
0
10
0
0
10
0
% K
% Leu:
0
0
0
20
0
0
10
0
10
0
0
50
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
10
60
0
0
60
0
0
0
10
0
20
0
10
0
% P
% Gln:
0
10
0
50
0
0
0
0
10
10
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
50
% R
% Ser:
20
0
0
0
10
0
10
60
0
10
10
0
10
10
20
% S
% Thr:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
50
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
10
0
0
0
0
0
60
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _